Nanoscatterer-Assisted Fluorescence Amplification Technique
Weak fluorescence signals, which are important in research and applications, are often masked by the background. Different amplification techniques are actively investigated. Here, a broadband, geometry-independent and flexible feedback scheme based on the random scattering of dielectric nanoparticl...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-10-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/13/21/2875 |
| _version_ | 1797631505849122816 |
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| author | Sylvain Bonnefond Antoine Reynaud Julie Cazareth Sophie Abélanet Massimo Vassalli Frédéric Brau Gian Luca Lippi |
| author_facet | Sylvain Bonnefond Antoine Reynaud Julie Cazareth Sophie Abélanet Massimo Vassalli Frédéric Brau Gian Luca Lippi |
| author_sort | Sylvain Bonnefond |
| collection | DOAJ |
| description | Weak fluorescence signals, which are important in research and applications, are often masked by the background. Different amplification techniques are actively investigated. Here, a broadband, geometry-independent and flexible feedback scheme based on the random scattering of dielectric nanoparticles allows the amplification of a fluorescence signal by partial trapping of the radiation within the sample volume. Amplification of up to a factor of 40 is experimentally demonstrated in ultrapure water with dispersed TiO<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mrow></mrow><mn>2</mn></msub></semantics></math></inline-formula> nanoparticles (30 to 50 nm in diameter) and fluorescein dye at 200 <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi mathvariant="sans-serif">μ</mi></semantics></math></inline-formula>mol concentration (pumped with 5 ns long, 3 mJ laser pulses at 490 nm). The measurements show a measurable reduction in linewidth at the emission peak, indicating that feedback-induced stimulated emission contributes to the large gain observed. |
| first_indexed | 2024-03-11T11:24:29Z |
| format | Article |
| id | doaj.art-97436fb909d645caa17d4a122cc2cf50 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-11T11:24:29Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-97436fb909d645caa17d4a122cc2cf502023-11-10T15:09:15ZengMDPI AGNanomaterials2079-49912023-10-011321287510.3390/nano13212875Nanoscatterer-Assisted Fluorescence Amplification TechniqueSylvain Bonnefond0Antoine Reynaud1Julie Cazareth2Sophie Abélanet3Massimo Vassalli4Frédéric Brau5Gian Luca Lippi6Université Côte d’Azur, UMR 7010 CNRS, Institut de Physique de Nice, 06560 Valbonne, FranceUniversité Côte d’Azur, UMR 7275 CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, 06560 Valbonne, FranceUniversité Côte d’Azur, UMR 7275 CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, 06560 Valbonne, FranceUniversité Côte d’Azur, UMR 7275 CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, 06560 Valbonne, FranceJames Watt School of Engineering, University of Glasgow, Glasgow G12 8LT, UKUniversité Côte d’Azur, UMR 7275 CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, 06560 Valbonne, FranceUniversité Côte d’Azur, UMR 7010 CNRS, Institut de Physique de Nice, 06560 Valbonne, FranceWeak fluorescence signals, which are important in research and applications, are often masked by the background. Different amplification techniques are actively investigated. Here, a broadband, geometry-independent and flexible feedback scheme based on the random scattering of dielectric nanoparticles allows the amplification of a fluorescence signal by partial trapping of the radiation within the sample volume. Amplification of up to a factor of 40 is experimentally demonstrated in ultrapure water with dispersed TiO<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mrow></mrow><mn>2</mn></msub></semantics></math></inline-formula> nanoparticles (30 to 50 nm in diameter) and fluorescein dye at 200 <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi mathvariant="sans-serif">μ</mi></semantics></math></inline-formula>mol concentration (pumped with 5 ns long, 3 mJ laser pulses at 490 nm). The measurements show a measurable reduction in linewidth at the emission peak, indicating that feedback-induced stimulated emission contributes to the large gain observed.https://www.mdpi.com/2079-4991/13/21/2875nanoparticlesmultiple scatteringlight amplificationoptical gainlinewidth narrowingstimulated emission |
| spellingShingle | Sylvain Bonnefond Antoine Reynaud Julie Cazareth Sophie Abélanet Massimo Vassalli Frédéric Brau Gian Luca Lippi Nanoscatterer-Assisted Fluorescence Amplification Technique Nanomaterials nanoparticles multiple scattering light amplification optical gain linewidth narrowing stimulated emission |
| title | Nanoscatterer-Assisted Fluorescence Amplification Technique |
| title_full | Nanoscatterer-Assisted Fluorescence Amplification Technique |
| title_fullStr | Nanoscatterer-Assisted Fluorescence Amplification Technique |
| title_full_unstemmed | Nanoscatterer-Assisted Fluorescence Amplification Technique |
| title_short | Nanoscatterer-Assisted Fluorescence Amplification Technique |
| title_sort | nanoscatterer assisted fluorescence amplification technique |
| topic | nanoparticles multiple scattering light amplification optical gain linewidth narrowing stimulated emission |
| url | https://www.mdpi.com/2079-4991/13/21/2875 |
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