Donor-derived Cell-free DNA Combined With Histology Improves Prediction of Estimated Glomerular Filtration Rate Over Time in Kidney Transplant Recipients Compared With Histology Alone

Donor-derived Cell-free DNA Combined With Histology Improves Prediction of Estimated Glomerular Filtration Rate Over Time in Kidney Transplant Recipients Compared With Histology Alone

Background. Higher Banff inflammation and chronicity scores on kidney transplant biopsies are associated with poorer graft survival, although histology alone has limitations in predicting outcomes. We investigated if integrating donor-derived cell-free DNA (dd-cfDNA, Allosure; CareDx, Inc.) with Ban...

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Main Authors: Edmund Huang, MD, Matthew Gillespie, PharmD, Noriko Ammerman, PharmD, Ashley Vo, PharmD, Kathlyn Lim, PharmD, Alice Peng, MD, Reiad Najjar, MD, Supreet Sethi, MD, Stanley C. Jordan, MD, James Mirocha, MS, Mark Haas, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2020-08-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001027

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