TLRs in COVID-19: How they drive immunopathology and the rationale for modulation

COVID-19 is both a viral illness and a disease of immunopathology. Proximal events within the innate immune system drive the balance between deleterious inflammation and viral clearance. We hypothesize that a divergence between the generation of excessive inflammation through over activation of the...

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Bibliographic Details
Main Authors: F. Linzee Mabrey, Eric D Morrell, Mark M Wurfel
Format: Article
Language:English
Published: SAGE Publishing 2021-10-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/17534259211051364