A case of anti--methyl--aspartate receptor encephalitis

Anti- N -methyl- d -aspartate receptor encephalitis is characterized by the clinical manifestation of neuropsychiatric symptoms, predominantly affecting young adults, and frequently associated with neoplasms. It is the second most common cause of autoimmune and paraneoplastic encephalitis. Early dia...

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Main Authors: Anna Misyail Abdul Rashid, Elmina Mohamad Mokhtar, Mohamad Syafeeq Faeez Md Noh
Format: Article
Language:English
Published: SAGE Publishing 2020-06-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X20926431
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author Anna Misyail Abdul Rashid
Elmina Mohamad Mokhtar
Mohamad Syafeeq Faeez Md Noh
author_facet Anna Misyail Abdul Rashid
Elmina Mohamad Mokhtar
Mohamad Syafeeq Faeez Md Noh
author_sort Anna Misyail Abdul Rashid
collection DOAJ
description Anti- N -methyl- d -aspartate receptor encephalitis is characterized by the clinical manifestation of neuropsychiatric symptoms, predominantly affecting young adults, and frequently associated with neoplasms. It is the second most common cause of autoimmune and paraneoplastic encephalitis. Early diagnosis is often missed, as patients are commonly diagnosed with psychiatric illnesses and are treated with antipsychotics – which rarely gives complete resolution of symptoms. Herein, we discuss a patient with mixed clinical, imaging, electroencephalogram, and laboratory findings, with an eventual diagnosis of anti- N -methyl- d -aspartate receptor encephalitis requiring immunotherapy and operative intervention.
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spelling doaj.art-9747de25f71340a5bb2496083cbe3fbd2022-12-21T23:05:55ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2020-06-01810.1177/2050313X20926431A case of anti--methyl--aspartate receptor encephalitisAnna Misyail Abdul Rashid0Elmina Mohamad Mokhtar1Mohamad Syafeeq Faeez Md Noh2Department of Medicine, Level 3, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, MalaysiaDepartment of Pathology, Hospital Serdang, Kajang, MalaysiaDepartment of Imaging, Level 3, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, MalaysiaAnti- N -methyl- d -aspartate receptor encephalitis is characterized by the clinical manifestation of neuropsychiatric symptoms, predominantly affecting young adults, and frequently associated with neoplasms. It is the second most common cause of autoimmune and paraneoplastic encephalitis. Early diagnosis is often missed, as patients are commonly diagnosed with psychiatric illnesses and are treated with antipsychotics – which rarely gives complete resolution of symptoms. Herein, we discuss a patient with mixed clinical, imaging, electroencephalogram, and laboratory findings, with an eventual diagnosis of anti- N -methyl- d -aspartate receptor encephalitis requiring immunotherapy and operative intervention.https://doi.org/10.1177/2050313X20926431
spellingShingle Anna Misyail Abdul Rashid
Elmina Mohamad Mokhtar
Mohamad Syafeeq Faeez Md Noh
A case of anti--methyl--aspartate receptor encephalitis
SAGE Open Medical Case Reports
title A case of anti--methyl--aspartate receptor encephalitis
title_full A case of anti--methyl--aspartate receptor encephalitis
title_fullStr A case of anti--methyl--aspartate receptor encephalitis
title_full_unstemmed A case of anti--methyl--aspartate receptor encephalitis
title_short A case of anti--methyl--aspartate receptor encephalitis
title_sort case of anti methyl aspartate receptor encephalitis
url https://doi.org/10.1177/2050313X20926431
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