Population-scale long-read sequencing uncovers transposable elements associated with gene expression variation and adaptive signatures in Drosophila
Even in well-studied species, there is still substantial natural genetic variation that has not been characterized. Here, the authors use long read sequencing to discover transposable elements in the Drosophila genome not detected by short read sequencing, and link them to gene expression.
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-29518-8 |
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author | Gabriel E. Rech Santiago Radío Sara Guirao-Rico Laura Aguilera Vivien Horvath Llewellyn Green Hannah Lindstadt Véronique Jamilloux Hadi Quesneville Josefa González |
author_facet | Gabriel E. Rech Santiago Radío Sara Guirao-Rico Laura Aguilera Vivien Horvath Llewellyn Green Hannah Lindstadt Véronique Jamilloux Hadi Quesneville Josefa González |
author_sort | Gabriel E. Rech |
collection | DOAJ |
description | Even in well-studied species, there is still substantial natural genetic variation that has not been characterized. Here, the authors use long read sequencing to discover transposable elements in the Drosophila genome not detected by short read sequencing, and link them to gene expression. |
first_indexed | 2024-04-14T08:32:17Z |
format | Article |
id | doaj.art-974aeaeb89bd46518065ccb417e58235 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-04-14T08:32:17Z |
publishDate | 2022-04-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-974aeaeb89bd46518065ccb417e582352022-12-22T02:03:52ZengNature PortfolioNature Communications2041-17232022-04-0113111610.1038/s41467-022-29518-8Population-scale long-read sequencing uncovers transposable elements associated with gene expression variation and adaptive signatures in DrosophilaGabriel E. Rech0Santiago Radío1Sara Guirao-Rico2Laura Aguilera3Vivien Horvath4Llewellyn Green5Hannah Lindstadt6Véronique Jamilloux7Hadi Quesneville8Josefa González9Institute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra)Institute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra)Institute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra)Institute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra)Institute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra)Institute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra)Institute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra)Université Paris-Saclay, INRAE, URGIUniversité Paris-Saclay, INRAE, URGIInstitute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra)Even in well-studied species, there is still substantial natural genetic variation that has not been characterized. Here, the authors use long read sequencing to discover transposable elements in the Drosophila genome not detected by short read sequencing, and link them to gene expression.https://doi.org/10.1038/s41467-022-29518-8 |
spellingShingle | Gabriel E. Rech Santiago Radío Sara Guirao-Rico Laura Aguilera Vivien Horvath Llewellyn Green Hannah Lindstadt Véronique Jamilloux Hadi Quesneville Josefa González Population-scale long-read sequencing uncovers transposable elements associated with gene expression variation and adaptive signatures in Drosophila Nature Communications |
title | Population-scale long-read sequencing uncovers transposable elements associated with gene expression variation and adaptive signatures in Drosophila |
title_full | Population-scale long-read sequencing uncovers transposable elements associated with gene expression variation and adaptive signatures in Drosophila |
title_fullStr | Population-scale long-read sequencing uncovers transposable elements associated with gene expression variation and adaptive signatures in Drosophila |
title_full_unstemmed | Population-scale long-read sequencing uncovers transposable elements associated with gene expression variation and adaptive signatures in Drosophila |
title_short | Population-scale long-read sequencing uncovers transposable elements associated with gene expression variation and adaptive signatures in Drosophila |
title_sort | population scale long read sequencing uncovers transposable elements associated with gene expression variation and adaptive signatures in drosophila |
url | https://doi.org/10.1038/s41467-022-29518-8 |
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