High SOX2 levels predict better outcome in non-small cell lung carcinomas.

High SOX2 levels predict better outcome in non-small cell lung carcinomas.

BACKGROUND: SOX2 is an embryonic developmental transcription factor, which is important in the development of the respiratory tract. SOX2 overexpression is associated with aggressive disease in several tumor types. However, SOX2 overexpression and gene amplification associates with favorable outcome...

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Bibliographic Details
Main Authors: Vamsidhar Velcheti, Kurt Schalper, Xiaopan Yao, Huan Cheng, Mehmet Kocoglu, Kavita Dhodapkar, Yanhong Deng, Scott Gettinger, David L Rimm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3631238?pdf=render

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