Cytotoxic and immunomodulatory potential of a novel [2-(4-(2,5-dimethyl-1H-pyrrol-1-yl)−1H-pyrazol-3-yl)pyridine] in myeloid leukemia

Cytotoxic and immunomodulatory potential of a novel [2-(4-(2,5-dimethyl-1H-pyrrol-1-yl)−1H-pyrazol-3-yl)pyridine] in myeloid leukemia

Cancer ranks among the leading causes of mortality worldwide. However, the efficacy of commercially available anticancer drugs is compromised by the emerging challenge of drug resistance. This study aimed to investigate the anticancer and immunomodulatory potential of a recently developed a novel [2...

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Bibliographic Details
Main Authors: Carlos Eduardo de Castro Alves, Georgyi Koidan, Anastasiia N. Hurieva, Alice de Freitas Gomes, Regiane Costa de Oliveira, Allyson Guimarães Costa, Antônio Luiz Ribeiro Boechat, André Correa de Oliveira, Serhii Zahorulko, Aleksandr Kostyuk, Gemilson Soares Pontes
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Anticancer
Myeloid leukemia
Pyridine synthesis
Immunomodulation
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223004894

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