ARTEMIN Promotes Oncogenicity and Resistance to 5-Fluorouracil in Colorectal Carcinoma by p44/42 MAPK Dependent Expression of CDH2

ARTEMIN Promotes Oncogenicity and Resistance to 5-Fluorouracil in Colorectal Carcinoma by p44/42 MAPK Dependent Expression of CDH2

ARTEMIN (ARTN), one of the glial-cell derived neurotrophic factor family of ligands, has been reported to be associated with a number of human malignancies. In this study, the enhanced expression of ARTN in colorectal carcinoma (CRC) was observed; the expression of ARTN positively correlated with ly...

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Bibliographic Details
Main Authors: Qiu-Shi Zhuang, Xin-Bao Sun, Qing-Yun Chong, Arindam Banerjee, Min Zhang, Zheng-Sheng Wu, Tao Zhu, Vijay Pandey, Peter E. Lobie
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
ARTEMIN
colorectal carcinoma
P44/42 MAPK
CDH2
metastasis
chemoresistance
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.712348/full

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