Cognitive decline and risk of dementia in older adults after diagnosis of chronic obstructive pulmonary disease
Abstract Cognitive screening has been proposed for older adults diagnosed with chronic obstructive pulmonary disease (COPD). Therefore, we examined the change over time in cognitive function and the risk of incident dementia in older adults after COPD diagnosis. A sample of 3,982 participants from t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-05-01
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| Series: | npj Primary Care Respiratory Medicine |
| Online Access: | https://doi.org/10.1038/s41533-023-00342-x |
| _version_ | 1797827655673839616 |
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| author | Aldana Rosso Tomas Månsson Karl Egervall Sölve Elmståhl Marieclaire Overton |
| author_facet | Aldana Rosso Tomas Månsson Karl Egervall Sölve Elmståhl Marieclaire Overton |
| author_sort | Aldana Rosso |
| collection | DOAJ |
| description | Abstract Cognitive screening has been proposed for older adults diagnosed with chronic obstructive pulmonary disease (COPD). Therefore, we examined the change over time in cognitive function and the risk of incident dementia in older adults after COPD diagnosis. A sample of 3,982 participants from the population-based cohort study Good Aging in Skåne was followed for 19 years, and 317 incident COPD cases were identified. The cognitive domains of episodic memory, executive function, and language were assessed using neuropsychological tests. Mixed models for repeated measures and a Cox model were implemented. Participants performed, on average, worse over time on all neuropsychological tests after COPD diagnosis in comparison to those without COPD, although statistical significance differences were only observed for episodic memory and language. The groups had a comparable risk of developing dementia. In conclusion, our results indicate that cognitive screening in the early stages of COPD may be of limited clinical relevance. |
| first_indexed | 2024-04-09T12:51:50Z |
| format | Article |
| id | doaj.art-975bfd438dbb4e10bad024835cb19efd |
| institution | Directory Open Access Journal |
| issn | 2055-1010 |
| language | English |
| last_indexed | 2024-04-09T12:51:50Z |
| publishDate | 2023-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Primary Care Respiratory Medicine |
| spelling | doaj.art-975bfd438dbb4e10bad024835cb19efd2023-05-14T11:08:36ZengNature Portfolionpj Primary Care Respiratory Medicine2055-10102023-05-013311710.1038/s41533-023-00342-xCognitive decline and risk of dementia in older adults after diagnosis of chronic obstructive pulmonary diseaseAldana Rosso0Tomas Månsson1Karl Egervall2Sölve Elmståhl3Marieclaire Overton4Division of Geriatric Medicine, Department of Clinical Sciences in Malmö, Lund UniversityDivision of Geriatric Medicine, Department of Clinical Sciences in Malmö, Lund UniversityDivision of Geriatric Medicine, Department of Clinical Sciences in Malmö, Lund UniversityDivision of Geriatric Medicine, Department of Clinical Sciences in Malmö, Lund UniversityDivision of Geriatric Medicine, Department of Clinical Sciences in Malmö, Lund UniversityAbstract Cognitive screening has been proposed for older adults diagnosed with chronic obstructive pulmonary disease (COPD). Therefore, we examined the change over time in cognitive function and the risk of incident dementia in older adults after COPD diagnosis. A sample of 3,982 participants from the population-based cohort study Good Aging in Skåne was followed for 19 years, and 317 incident COPD cases were identified. The cognitive domains of episodic memory, executive function, and language were assessed using neuropsychological tests. Mixed models for repeated measures and a Cox model were implemented. Participants performed, on average, worse over time on all neuropsychological tests after COPD diagnosis in comparison to those without COPD, although statistical significance differences were only observed for episodic memory and language. The groups had a comparable risk of developing dementia. In conclusion, our results indicate that cognitive screening in the early stages of COPD may be of limited clinical relevance.https://doi.org/10.1038/s41533-023-00342-x |
| spellingShingle | Aldana Rosso Tomas Månsson Karl Egervall Sölve Elmståhl Marieclaire Overton Cognitive decline and risk of dementia in older adults after diagnosis of chronic obstructive pulmonary disease npj Primary Care Respiratory Medicine |
| title | Cognitive decline and risk of dementia in older adults after diagnosis of chronic obstructive pulmonary disease |
| title_full | Cognitive decline and risk of dementia in older adults after diagnosis of chronic obstructive pulmonary disease |
| title_fullStr | Cognitive decline and risk of dementia in older adults after diagnosis of chronic obstructive pulmonary disease |
| title_full_unstemmed | Cognitive decline and risk of dementia in older adults after diagnosis of chronic obstructive pulmonary disease |
| title_short | Cognitive decline and risk of dementia in older adults after diagnosis of chronic obstructive pulmonary disease |
| title_sort | cognitive decline and risk of dementia in older adults after diagnosis of chronic obstructive pulmonary disease |
| url | https://doi.org/10.1038/s41533-023-00342-x |
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