Downregulation of miR-542-3p promotes osteogenic transition of vascular smooth muscle cells in the aging rat by targeting BMP7

Abstract Background Aging is believed to have a close association with cardiovascular diseases, resulting in various pathological alterations in blood vessels, including vascular cell phenotypic shifts. In aging vessels, the microRNA(miRNA)-mediated mechanism regulating the vascular smooth muscle ce...

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Bibliographic Details
Main Authors: Huan Liu, Hongwei Wang, Sijin Yang, Dehui Qian
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Human Genomics
Subjects:
Online Access:https://doi.org/10.1186/s40246-019-0245-z

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