Isolated Leptomeningeal Enhancement in Anti-N-Methyl D-Aspartate Receptor Encephalitis: The Diagnostic Value of Contrast-Enhanced Fluid-Attenuated Inversion Recovery Imaging
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a common autoimmune encephalitis that is noted to be a severe but treatable disease entity. Patients with anti-NMDAR encephalitis often develop psychotic symptoms, including delusions, hallucinations, and paranoia, as well as memory...
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Format: | Article |
Language: | English |
Published: |
The Korean Society of Radiology
2022-07-01
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Series: | 대한영상의학회지 |
Online Access: | https://doi.org/10.3348/jksr.2021.0098 |
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author | Jun Kyeong Park, Eun Ja Lee, Kwang Ki Kim |
author_facet | Jun Kyeong Park, Eun Ja Lee, Kwang Ki Kim |
author_sort | Jun Kyeong Park, Eun Ja Lee, Kwang Ki Kim |
collection | DOAJ |
description | Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a common autoimmune encephalitis
that is noted to be a severe but treatable disease entity. Patients with anti-NMDAR
encephalitis often develop psychotic symptoms, including delusions, hallucinations, and paranoia,
as well as memory impairment and persistent loss of attention. However, MRI findings in
such patients show no abnormalities in most cases. Although typical brain abnormality features,
known as T2 hyperintensities, involve the brain parenchyma and contrast enhancement
at the cerebral cortex or overlying meninges, isolated leptomeningeal enhancement has been
rarely reported in anti-NMDAR encephalitis. Herein, we report a patient with anti-NMDAR encephalitis
who presented with isolated leptomeningeal enhancement, additionally showing
the diagnostic value of contrast-enhanced fluid-attenuated inversion recovery imaging. |
first_indexed | 2024-12-10T21:19:30Z |
format | Article |
id | doaj.art-976106dc438b41bc9f1d4a853435a642 |
institution | Directory Open Access Journal |
issn | 2288-2928 |
language | English |
last_indexed | 2024-12-10T21:19:30Z |
publishDate | 2022-07-01 |
publisher | The Korean Society of Radiology |
record_format | Article |
series | 대한영상의학회지 |
spelling | doaj.art-976106dc438b41bc9f1d4a853435a6422022-12-22T01:33:10ZengThe Korean Society of Radiology대한영상의학회지2288-29282022-07-01834945950https://doi.org/10.3348/jksr.2021.0098Isolated Leptomeningeal Enhancement in Anti-N-Methyl D-Aspartate Receptor Encephalitis: The Diagnostic Value of Contrast-Enhanced Fluid-Attenuated Inversion Recovery ImagingJun Kyeong Park, Eun Ja Lee, Kwang Ki KimAnti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a common autoimmune encephalitis that is noted to be a severe but treatable disease entity. Patients with anti-NMDAR encephalitis often develop psychotic symptoms, including delusions, hallucinations, and paranoia, as well as memory impairment and persistent loss of attention. However, MRI findings in such patients show no abnormalities in most cases. Although typical brain abnormality features, known as T2 hyperintensities, involve the brain parenchyma and contrast enhancement at the cerebral cortex or overlying meninges, isolated leptomeningeal enhancement has been rarely reported in anti-NMDAR encephalitis. Herein, we report a patient with anti-NMDAR encephalitis who presented with isolated leptomeningeal enhancement, additionally showing the diagnostic value of contrast-enhanced fluid-attenuated inversion recovery imaging.https://doi.org/10.3348/jksr.2021.0098 |
spellingShingle | Jun Kyeong Park, Eun Ja Lee, Kwang Ki Kim Isolated Leptomeningeal Enhancement in Anti-N-Methyl D-Aspartate Receptor Encephalitis: The Diagnostic Value of Contrast-Enhanced Fluid-Attenuated Inversion Recovery Imaging 대한영상의학회지 |
title | Isolated Leptomeningeal Enhancement in Anti-N-Methyl D-Aspartate Receptor Encephalitis: The Diagnostic Value of Contrast-Enhanced Fluid-Attenuated Inversion Recovery Imaging |
title_full | Isolated Leptomeningeal Enhancement in Anti-N-Methyl D-Aspartate Receptor Encephalitis: The Diagnostic Value of Contrast-Enhanced Fluid-Attenuated Inversion Recovery Imaging |
title_fullStr | Isolated Leptomeningeal Enhancement in Anti-N-Methyl D-Aspartate Receptor Encephalitis: The Diagnostic Value of Contrast-Enhanced Fluid-Attenuated Inversion Recovery Imaging |
title_full_unstemmed | Isolated Leptomeningeal Enhancement in Anti-N-Methyl D-Aspartate Receptor Encephalitis: The Diagnostic Value of Contrast-Enhanced Fluid-Attenuated Inversion Recovery Imaging |
title_short | Isolated Leptomeningeal Enhancement in Anti-N-Methyl D-Aspartate Receptor Encephalitis: The Diagnostic Value of Contrast-Enhanced Fluid-Attenuated Inversion Recovery Imaging |
title_sort | isolated leptomeningeal enhancement in anti n methyl d aspartate receptor encephalitis the diagnostic value of contrast enhanced fluid attenuated inversion recovery imaging |
url | https://doi.org/10.3348/jksr.2021.0098 |
work_keys_str_mv | AT junkyeongparkeunjaleekwangkikim isolatedleptomeningealenhancementinantinmethyldaspartatereceptorencephalitisthediagnosticvalueofcontrastenhancedfluidattenuatedinversionrecoveryimaging |