Causes of hypoglycemia

Introduction: Hypoglycemia is metabolic state of ogranism characterized by abnormally low blood glucose level. Due to International Hypoglycemia Study Group (2017) and following Polish Diabetes Association Guidelines is is recognized with serum glucose below 70mg/dl – with or without accompanying sy...

Full description

Bibliographic Details
Main Authors: Ewa Tywanek, Paulina Trojanowska, Magdalena Woźniak, Jakub Wronecki, Agnieszka Zwolak, Robert Jan Łuczyk
Format: Article
Language:English
Published: Kazimierz Wielki University 2019-09-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:http://www.ojs.ukw.edu.pl/index.php/johs/article/view/7514
_version_ 1818277384239972352
author Ewa Tywanek
Paulina Trojanowska
Magdalena Woźniak
Jakub Wronecki
Agnieszka Zwolak
Robert Jan Łuczyk
author_facet Ewa Tywanek
Paulina Trojanowska
Magdalena Woźniak
Jakub Wronecki
Agnieszka Zwolak
Robert Jan Łuczyk
author_sort Ewa Tywanek
collection DOAJ
description Introduction: Hypoglycemia is metabolic state of ogranism characterized by abnormally low blood glucose level. Due to International Hypoglycemia Study Group (2017) and following Polish Diabetes Association Guidelines is is recognized with serum glucose below 70mg/dl – with or without accompanying symptoms, such as tremor or altered mental status or even hypoglycemic coma. Symptoms mentioned above may have huge impact on personal or social functioning of the patient. Purpose: To present a list of known causes of hypoglycemic state. Summary: Hypoglycemia is quite unpleasant and dangerous metabolic state that may be caused by multiple etiological factors. The most common cause of this condition is useing too much insulin in treatment of diabetes mellitus. Other diabetic drugs, such us for example sulphonylureas may result in hypoglycemia. Chemicals containing sulfhydryl group in their structure may result in severe hypoglycemia in progress of Insulin Autoimmune Syndrome (IAS). Organic basis of hypoglycemia due to increased amount of producing insulin may be recognized, in progress of pancreatic secreting tumor, called insulinoma. From the other hand functional abnormality of carbohydrate metabolism may be found. It’s called functional hypoglycemia and may develop due to presence of hyperinsulism and insulin resistance secondary to incorrect lifestyle and diet. Partly organic and functional cause of hypogycemia may be recognized after bariatric surgery. Fairy seldom hypoglycemia with low blood insulin level may be found. The example of this state constitutes Dodge-Potter Syndrome, when tumor is able to produce insulin-growth factor 2 (IGF-2) stimulating insulin receptor, what results in serum glucose reduction. Hypoglycemia, as very adverse state for human organism, should be closely diagnose and efficiently treated.
first_indexed 2024-12-12T23:00:41Z
format Article
id doaj.art-9762e97739ee4fc8828f0f2bf772d835
institution Directory Open Access Journal
issn 2391-8306
language English
last_indexed 2024-12-12T23:00:41Z
publishDate 2019-09-01
publisher Kazimierz Wielki University
record_format Article
series Journal of Education, Health and Sport
spelling doaj.art-9762e97739ee4fc8828f0f2bf772d8352022-12-22T00:08:50ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062019-09-019990591110.5281/zenodo.34606256608Causes of hypoglycemiaEwa Tywanek0Paulina Trojanowska1Magdalena Woźniak2Jakub Wronecki3Agnieszka Zwolak4Robert Jan Łuczyk5Chair of Internal Medicine and Department of Internal Medicine in Nursing, Medical University of LublinDepartment of Pediatric Neurology, Medical University of LublinChair and Department of Endocrinology, Medical University of LublinChair and Department of Gastroenterology, Medical University of LublinChair of Internal Medicine and Department of Internal Medicine in Nursing, Medical University of LublinChair of Internal Medicine and Department of Internal Medicine in Nursing, Medical University of LublinIntroduction: Hypoglycemia is metabolic state of ogranism characterized by abnormally low blood glucose level. Due to International Hypoglycemia Study Group (2017) and following Polish Diabetes Association Guidelines is is recognized with serum glucose below 70mg/dl – with or without accompanying symptoms, such as tremor or altered mental status or even hypoglycemic coma. Symptoms mentioned above may have huge impact on personal or social functioning of the patient. Purpose: To present a list of known causes of hypoglycemic state. Summary: Hypoglycemia is quite unpleasant and dangerous metabolic state that may be caused by multiple etiological factors. The most common cause of this condition is useing too much insulin in treatment of diabetes mellitus. Other diabetic drugs, such us for example sulphonylureas may result in hypoglycemia. Chemicals containing sulfhydryl group in their structure may result in severe hypoglycemia in progress of Insulin Autoimmune Syndrome (IAS). Organic basis of hypoglycemia due to increased amount of producing insulin may be recognized, in progress of pancreatic secreting tumor, called insulinoma. From the other hand functional abnormality of carbohydrate metabolism may be found. It’s called functional hypoglycemia and may develop due to presence of hyperinsulism and insulin resistance secondary to incorrect lifestyle and diet. Partly organic and functional cause of hypogycemia may be recognized after bariatric surgery. Fairy seldom hypoglycemia with low blood insulin level may be found. The example of this state constitutes Dodge-Potter Syndrome, when tumor is able to produce insulin-growth factor 2 (IGF-2) stimulating insulin receptor, what results in serum glucose reduction. Hypoglycemia, as very adverse state for human organism, should be closely diagnose and efficiently treated.http://www.ojs.ukw.edu.pl/index.php/johs/article/view/7514hypoglycemiadrug-induced hypoglycemiainsulinomanon-islet cell tumors hypoglycemiadodge-potter syndromepost-bariatric hypoglycemia
spellingShingle Ewa Tywanek
Paulina Trojanowska
Magdalena Woźniak
Jakub Wronecki
Agnieszka Zwolak
Robert Jan Łuczyk
Causes of hypoglycemia
Journal of Education, Health and Sport
hypoglycemia
drug-induced hypoglycemia
insulinoma
non-islet cell tumors hypoglycemia
dodge-potter syndrome
post-bariatric hypoglycemia
title Causes of hypoglycemia
title_full Causes of hypoglycemia
title_fullStr Causes of hypoglycemia
title_full_unstemmed Causes of hypoglycemia
title_short Causes of hypoglycemia
title_sort causes of hypoglycemia
topic hypoglycemia
drug-induced hypoglycemia
insulinoma
non-islet cell tumors hypoglycemia
dodge-potter syndrome
post-bariatric hypoglycemia
url http://www.ojs.ukw.edu.pl/index.php/johs/article/view/7514
work_keys_str_mv AT ewatywanek causesofhypoglycemia
AT paulinatrojanowska causesofhypoglycemia
AT magdalenawozniak causesofhypoglycemia
AT jakubwronecki causesofhypoglycemia
AT agnieszkazwolak causesofhypoglycemia
AT robertjanłuczyk causesofhypoglycemia