Relationship between Heart Disease and Liver Disease: A Two-Way Street

In clinical practice, combined heart and liver dysfunctions coexist in the setting of the main heart and liver diseases because of complex cardiohepatic interactions. It is becoming increasingly crucial to identify these interactions between heart and liver in order to ensure an effective management...

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Main Authors: Hamza El Hadi, Angelo Di Vincenzo, Roberto Vettor, Marco Rossato
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/3/567
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author Hamza El Hadi
Angelo Di Vincenzo
Roberto Vettor
Marco Rossato
author_facet Hamza El Hadi
Angelo Di Vincenzo
Roberto Vettor
Marco Rossato
author_sort Hamza El Hadi
collection DOAJ
description In clinical practice, combined heart and liver dysfunctions coexist in the setting of the main heart and liver diseases because of complex cardiohepatic interactions. It is becoming increasingly crucial to identify these interactions between heart and liver in order to ensure an effective management of patients with heart or liver disease to provide an improvement in overall prognosis and therapy. In this review, we aim to summarize the cross-talk between heart and liver in the setting of the main pathologic conditions affecting these organs. Accordingly, we present the clinical manifestation, biochemical profiles, and histological findings of cardiogenic ischemic hepatitis and congestive hepatopathy due to acute and chronic heart failure, respectively. In addition, we discuss the main features of cardiac dysfunction in the setting of liver cirrhosis, nonalcoholic fatty liver disease, and those following liver transplantation.
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spelling doaj.art-97641d8ec6ee42e08568de88e20953f52023-09-02T17:59:18ZengMDPI AGCells2073-44092020-02-019356710.3390/cells9030567cells9030567Relationship between Heart Disease and Liver Disease: A Two-Way StreetHamza El Hadi0Angelo Di Vincenzo1Roberto Vettor2Marco Rossato3Internal Medicine 3, Department of Medicine - DIMED, University of Padova, Via Giustiniani2, 35100 Padova, ItalyInternal Medicine 3, Department of Medicine - DIMED, University of Padova, Via Giustiniani2, 35100 Padova, ItalyInternal Medicine 3, Department of Medicine - DIMED, University of Padova, Via Giustiniani2, 35100 Padova, ItalyInternal Medicine 3, Department of Medicine - DIMED, University of Padova, Via Giustiniani2, 35100 Padova, ItalyIn clinical practice, combined heart and liver dysfunctions coexist in the setting of the main heart and liver diseases because of complex cardiohepatic interactions. It is becoming increasingly crucial to identify these interactions between heart and liver in order to ensure an effective management of patients with heart or liver disease to provide an improvement in overall prognosis and therapy. In this review, we aim to summarize the cross-talk between heart and liver in the setting of the main pathologic conditions affecting these organs. Accordingly, we present the clinical manifestation, biochemical profiles, and histological findings of cardiogenic ischemic hepatitis and congestive hepatopathy due to acute and chronic heart failure, respectively. In addition, we discuss the main features of cardiac dysfunction in the setting of liver cirrhosis, nonalcoholic fatty liver disease, and those following liver transplantation.https://www.mdpi.com/2073-4409/9/3/567heart failurearrhythmiacongestive hepatopathycardiogenic ischemic hepatitiscirrhotic cardiomyopathyliver transplantationnonalcoholic fatty liver disease
spellingShingle Hamza El Hadi
Angelo Di Vincenzo
Roberto Vettor
Marco Rossato
Relationship between Heart Disease and Liver Disease: A Two-Way Street
Cells
heart failure
arrhythmia
congestive hepatopathy
cardiogenic ischemic hepatitis
cirrhotic cardiomyopathy
liver transplantation
nonalcoholic fatty liver disease
title Relationship between Heart Disease and Liver Disease: A Two-Way Street
title_full Relationship between Heart Disease and Liver Disease: A Two-Way Street
title_fullStr Relationship between Heart Disease and Liver Disease: A Two-Way Street
title_full_unstemmed Relationship between Heart Disease and Liver Disease: A Two-Way Street
title_short Relationship between Heart Disease and Liver Disease: A Two-Way Street
title_sort relationship between heart disease and liver disease a two way street
topic heart failure
arrhythmia
congestive hepatopathy
cardiogenic ischemic hepatitis
cirrhotic cardiomyopathy
liver transplantation
nonalcoholic fatty liver disease
url https://www.mdpi.com/2073-4409/9/3/567
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AT angelodivincenzo relationshipbetweenheartdiseaseandliverdiseaseatwowaystreet
AT robertovettor relationshipbetweenheartdiseaseandliverdiseaseatwowaystreet
AT marcorossato relationshipbetweenheartdiseaseandliverdiseaseatwowaystreet