Catecholaminergic Gene Polymorphisms Are Associated with GI Symptoms and Morphological Brain Changes in Irritable Bowel Syndrome.

Catecholaminergic Gene Polymorphisms Are Associated with GI Symptoms and Morphological Brain Changes in Irritable Bowel Syndrome.

Genetic and environmental factors contribute to the pathophysiology of irritable bowel syndrome (IBS). In particular, early adverse life events (EALs) and the catecholaminergic system have been implicated.To investigate whether catecholaminergic SNPs with or without interacting with EALs are associa...

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Bibliographic Details
Main Authors: Alexa Orand, Arpana Gupta, Wendy Shih, Angela P Presson, Christian Hammer, Beate Niesler, Nuwanthi Heendeniya, Emeran A Mayer, Lin Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4546052?pdf=render

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