Proposal of reference values for transverse cerebellar diameter in Korean fetuses and comparison with other countries
Background: In Korea, fetuses are currently assessed using ultrasound data collected from foreign subjects. This study aimed to propose independent reference values for the transverse cerebellar diameter (TCD) in Korean fetuses to predict gestational age (GA) and compare the TCD values among differe...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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IMR Press
2021-10-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/CEOG/48/5/10.31083/j.ceog4805169 |
| _version_ | 1828747989585231872 |
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| author | Sung-Hee Yang Chul-Hwan Hwang Hyun-Sook An Dong-Yeon Lee |
| author_facet | Sung-Hee Yang Chul-Hwan Hwang Hyun-Sook An Dong-Yeon Lee |
| author_sort | Sung-Hee Yang |
| collection | DOAJ |
| description | Background: In Korea, fetuses are currently assessed using ultrasound data collected from foreign subjects. This study aimed to propose independent reference values for the transverse cerebellar diameter (TCD) in Korean fetuses to predict gestational age (GA) and compare the TCD values among different countries. Methods: A total of 1819 healthy singletons with GAs of 15–37 weeks were retrospectively analyzed. The TCD was measured in the transcerebellar plane of the fetal head. TCD percentiles were calculated for different GAs, and a regression model was created to predict GA. Bland–Altman analysis was performed to examine the differences in the mean TCD and variations in the TCD among different countries. Results: The TCD ranged from 1.48 to 4.76 cm with a mean of 2.7 ± 0.91 cm. In the regression model of TCD (cm) = 0.129 GA (weeks) – 0.527 (95% confidence interval 0.129–0.130, p < 0.001), the TCD explained 98.4% of the variance in GA. Significant differences in the mean TCD were found between Korea, the United States, the United Kingdom, Hong Kong, and India. TCD variations increased as the mean TCD increased. Conclusions: Fetal TCD is an important biometric index for predicting GA. Ethnic differences must be considered when using fetal TCD. |
| first_indexed | 2024-04-14T04:53:13Z |
| format | Article |
| id | doaj.art-976988099b0b4ebb945c26416d07d9bb |
| institution | Directory Open Access Journal |
| issn | 0390-6663 |
| language | English |
| last_indexed | 2024-04-14T04:53:13Z |
| publishDate | 2021-10-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj.art-976988099b0b4ebb945c26416d07d9bb2022-12-22T02:11:14ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632021-10-014851056106010.31083/j.ceog4805169S0390-6663(21)00008-7Proposal of reference values for transverse cerebellar diameter in Korean fetuses and comparison with other countriesSung-Hee Yang0Chul-Hwan Hwang1Hyun-Sook An2Dong-Yeon Lee3Department of Radiological Science, College of Health Sciences, Catholic University of Pusan, 46252 Busan, Republic of KoreaDepartments of Radiology, Masan University, 51217 Gyeongsangnam-do, Republic of KoreaDepartment of Obstetrics and Gynecology, Ilsin Christian Hospital, 48724 Busan, Republic of KoreaDepartment of Radiological Science, College of Nursing, Healthcare Sciences & Human Ecology, Dong-eui University, 47340 Busan, Republic of KoreaBackground: In Korea, fetuses are currently assessed using ultrasound data collected from foreign subjects. This study aimed to propose independent reference values for the transverse cerebellar diameter (TCD) in Korean fetuses to predict gestational age (GA) and compare the TCD values among different countries. Methods: A total of 1819 healthy singletons with GAs of 15–37 weeks were retrospectively analyzed. The TCD was measured in the transcerebellar plane of the fetal head. TCD percentiles were calculated for different GAs, and a regression model was created to predict GA. Bland–Altman analysis was performed to examine the differences in the mean TCD and variations in the TCD among different countries. Results: The TCD ranged from 1.48 to 4.76 cm with a mean of 2.7 ± 0.91 cm. In the regression model of TCD (cm) = 0.129 GA (weeks) – 0.527 (95% confidence interval 0.129–0.130, p < 0.001), the TCD explained 98.4% of the variance in GA. Significant differences in the mean TCD were found between Korea, the United States, the United Kingdom, Hong Kong, and India. TCD variations increased as the mean TCD increased. Conclusions: Fetal TCD is an important biometric index for predicting GA. Ethnic differences must be considered when using fetal TCD.https://www.imrpress.com/journal/CEOG/48/5/10.31083/j.ceog4805169gestational agestandard valuetransverse cerebellar diameter |
| spellingShingle | Sung-Hee Yang Chul-Hwan Hwang Hyun-Sook An Dong-Yeon Lee Proposal of reference values for transverse cerebellar diameter in Korean fetuses and comparison with other countries Clinical and Experimental Obstetrics & Gynecology gestational age standard value transverse cerebellar diameter |
| title | Proposal of reference values for transverse cerebellar diameter in Korean fetuses and comparison with other countries |
| title_full | Proposal of reference values for transverse cerebellar diameter in Korean fetuses and comparison with other countries |
| title_fullStr | Proposal of reference values for transverse cerebellar diameter in Korean fetuses and comparison with other countries |
| title_full_unstemmed | Proposal of reference values for transverse cerebellar diameter in Korean fetuses and comparison with other countries |
| title_short | Proposal of reference values for transverse cerebellar diameter in Korean fetuses and comparison with other countries |
| title_sort | proposal of reference values for transverse cerebellar diameter in korean fetuses and comparison with other countries |
| topic | gestational age standard value transverse cerebellar diameter |
| url | https://www.imrpress.com/journal/CEOG/48/5/10.31083/j.ceog4805169 |
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