Gastroesophageal reflux in children with chronic recurrent cough
Background Gastroesophageal reflux (GER) is reported to be one of the most common causes of chronic recurrent cough (CRC). In Indonesia, so far there is no published data concerning GER in children with CRC. Objectives To determine the prevalence of GER in children with CRC in general, and asthma in...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Indonesian Pediatric Society Publishing House
2016-10-01
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| Series: | Paediatrica Indonesiana |
| Subjects: | |
| Online Access: | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/778 |
| _version_ | 1819067418312441856 |
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| author | Mardjanis Said Rianita Syamsu Taralan Tambunan Badriul Hegar |
| author_facet | Mardjanis Said Rianita Syamsu Taralan Tambunan Badriul Hegar |
| author_sort | Mardjanis Said |
| collection | DOAJ |
| description | Background Gastroesophageal reflux (GER) is reported to be
one of the most common causes of chronic recurrent cough (CRC).
In Indonesia, so far there is no published data concerning GER in
children with CRC.
Objectives To determine the prevalence of GER in children with
CRC in general, and asthma in particular; and to describe the clini-
cal profile associated with GER in these children.
Methods This was a cross sectional study on children with CRC
who were investigated for GER using 24-hour esophageal pH
monitoring. GER was graded based on reflux index (RI) stated in
pHmetry results i.e., mild (RI=5-10%), moderate (RI>10-20%), and
severe (RI>20%).
Results Among 48 children with CRC, GER was detected in 22
(46%) of them (mild GER in 14, moderate in 3, and severe in 5
children). In 35 children with asthma, which is the most frequent
cause of CRC in our hospital, GER was detected in 15. The preva-
lence of GER increased parallel with the frequency of cough epi-
sodes i.e., 10/27 in children with infrequent episodes of cough, 4/
10 in children with frequent episodes of cough, and 8/11 in chil-
dren with persistent cough. Clinical profiles associated with GER
in these children were persistent/ frequent episodes of CRC and
undernutrition.
Conclusions The prevalence of GER in children with CRC was
46%, and in those with asthma was 15/35. The clinical profiles
associated with GER are persistent/frequent episodes of CRC
and undernutrition |
| first_indexed | 2024-12-21T16:17:56Z |
| format | Article |
| id | doaj.art-9769c880a859411bbb604b89925f6071 |
| institution | Directory Open Access Journal |
| issn | 0030-9311 2338-476X |
| language | English |
| last_indexed | 2024-12-21T16:17:56Z |
| publishDate | 2016-10-01 |
| publisher | Indonesian Pediatric Society Publishing House |
| record_format | Article |
| series | Paediatrica Indonesiana |
| spelling | doaj.art-9769c880a859411bbb604b89925f60712022-12-21T18:57:38ZengIndonesian Pediatric Society Publishing HousePaediatrica Indonesiana0030-93112338-476X2016-10-01445201510.14238/pi44.5.2004.201-5641Gastroesophageal reflux in children with chronic recurrent coughMardjanis SaidRianita SyamsuTaralan TambunanBadriul HegarBackground Gastroesophageal reflux (GER) is reported to be one of the most common causes of chronic recurrent cough (CRC). In Indonesia, so far there is no published data concerning GER in children with CRC. Objectives To determine the prevalence of GER in children with CRC in general, and asthma in particular; and to describe the clini- cal profile associated with GER in these children. Methods This was a cross sectional study on children with CRC who were investigated for GER using 24-hour esophageal pH monitoring. GER was graded based on reflux index (RI) stated in pHmetry results i.e., mild (RI=5-10%), moderate (RI>10-20%), and severe (RI>20%). Results Among 48 children with CRC, GER was detected in 22 (46%) of them (mild GER in 14, moderate in 3, and severe in 5 children). In 35 children with asthma, which is the most frequent cause of CRC in our hospital, GER was detected in 15. The preva- lence of GER increased parallel with the frequency of cough epi- sodes i.e., 10/27 in children with infrequent episodes of cough, 4/ 10 in children with frequent episodes of cough, and 8/11 in chil- dren with persistent cough. Clinical profiles associated with GER in these children were persistent/ frequent episodes of CRC and undernutrition. Conclusions The prevalence of GER in children with CRC was 46%, and in those with asthma was 15/35. The clinical profiles associated with GER are persistent/frequent episodes of CRC and undernutritionhttps://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/778gastroesophageal refluxchronic coughrecurrent coughasthmachildrenprevalence24-hour esophageal monitoring |
| spellingShingle | Mardjanis Said Rianita Syamsu Taralan Tambunan Badriul Hegar Gastroesophageal reflux in children with chronic recurrent cough Paediatrica Indonesiana gastroesophageal reflux chronic cough recurrent cough asthma children prevalence 24-hour esophageal monitoring |
| title | Gastroesophageal reflux in children with chronic recurrent cough |
| title_full | Gastroesophageal reflux in children with chronic recurrent cough |
| title_fullStr | Gastroesophageal reflux in children with chronic recurrent cough |
| title_full_unstemmed | Gastroesophageal reflux in children with chronic recurrent cough |
| title_short | Gastroesophageal reflux in children with chronic recurrent cough |
| title_sort | gastroesophageal reflux in children with chronic recurrent cough |
| topic | gastroesophageal reflux chronic cough recurrent cough asthma children prevalence 24-hour esophageal monitoring |
| url | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/778 |
| work_keys_str_mv | AT mardjanissaid gastroesophagealrefluxinchildrenwithchronicrecurrentcough AT rianitasyamsu gastroesophagealrefluxinchildrenwithchronicrecurrentcough AT taralantambunan gastroesophagealrefluxinchildrenwithchronicrecurrentcough AT badriulhegar gastroesophagealrefluxinchildrenwithchronicrecurrentcough |