AMPK activation improves recovery from pneumonia-induced lung injury via reduction of er-stress and apoptosis in alveolar epithelial cells

AMPK activation improves recovery from pneumonia-induced lung injury via reduction of er-stress and apoptosis in alveolar epithelial cells

Abstract Background Bacterial pneumonia and related lung injury are among the most frequent causes of mortality in intensive care units, but also inflict serious and prolonged respiratory complications among survivors. Given that endoplasmic reticulum (ER) stress is a hallmark of sepsis-related alve...

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Bibliographic Details
Main Authors: Eugene Becker, Maroof Husain, Nathaniel Bone, Samuel Smith, Peter Morris, Jaroslaw W. Zmijewski
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Respiratory Research
Subjects:
Bacterial infections
Pneumonia
Endoplasmic reticulum
Mitochondria
Alveolar epithelial cells
Efferocytosis
Online Access:https://doi.org/10.1186/s12931-023-02483-6

Internet

https://doi.org/10.1186/s12931-023-02483-6

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