AMPK activation improves recovery from pneumonia-induced lung injury via reduction of er-stress and apoptosis in alveolar epithelial cells
Abstract Background Bacterial pneumonia and related lung injury are among the most frequent causes of mortality in intensive care units, but also inflict serious and prolonged respiratory complications among survivors. Given that endoplasmic reticulum (ER) stress is a hallmark of sepsis-related alve...
Main Authors: | Eugene Becker, Maroof Husain, Nathaniel Bone, Samuel Smith, Peter Morris, Jaroslaw W. Zmijewski |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-07-01
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Series: | Respiratory Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12931-023-02483-6 |
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