Assessment of Motor Cortex in Active, Passive and Imagery Wrist Movement using Functional MRI
Background: Functional Magnetic resonance imaging (fMRI) measures the small fluctuation of blood flow happening during task-fMRI in brain regions. Objective: This research investigated these active, imagery and passive movements in volunteers design to permit a comparison of their capabilities in ac...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2021-08-01
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| Series: | Journal of Biomedical Physics and Engineering |
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| Online Access: | https://jbpe.sums.ac.ir/article_46458_5b48143a5722f1f93261fcabab16e26c.pdf |
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| author | Hamid Sharini Shokufeh Zolghadriha Nader Riyahi Alam Maziar Jalalvandi Hamid Khabiri Hossein Arabalibeik Mohadeseh Nadimi |
| author_facet | Hamid Sharini Shokufeh Zolghadriha Nader Riyahi Alam Maziar Jalalvandi Hamid Khabiri Hossein Arabalibeik Mohadeseh Nadimi |
| author_sort | Hamid Sharini |
| collection | DOAJ |
| description | Background: Functional Magnetic resonance imaging (fMRI) measures the small fluctuation of blood flow happening during task-fMRI in brain regions. Objective: This research investigated these active, imagery and passive movements in volunteers design to permit a comparison of their capabilities in activating the brain areas.Material and Methods: In this applied research, the activity of the motor cortex during the right-wrist movement was evaluated in 10 normal volunteers under active, passive, and imagery conditions. T2* weighted, three-dimensional functional images were acquired using a BOLD sensitive gradient-echo EPI (echo planar imaging) sequence with echo time (TE) of 30 ms and repetition time (TR) of 2000 ms. The functional data, which included 248 volumes per subject and condition, were acquired using the blocked design paradigm. The images were analyzed by the SPM12 toolbox, MATLAB software. Results: The findings determined a significant increase in signal intensity of the motor cortex while performing the test compared to the rest time (p < 0.05). It was also observed that the active areas in hand representation of the motor cortex are different in terms of locations and the number of voxels in different wrist directions. Moreover, the findings showed that the position of active centers in the brain is different in active, passive, and imagery conditions. Conclusion: Results confirm that primary motor cortex neurons play an essential role in the processing of complex information and are designed to control the direction of movement. It seems that the findings of this study can be applied for rehabilitation studies. |
| first_indexed | 2024-12-22T08:03:38Z |
| format | Article |
| id | doaj.art-976d9a8a65364cae9ba763145305485d |
| institution | Directory Open Access Journal |
| issn | 2251-7200 2251-7200 |
| language | English |
| last_indexed | 2024-12-22T08:03:38Z |
| publishDate | 2021-08-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Journal of Biomedical Physics and Engineering |
| spelling | doaj.art-976d9a8a65364cae9ba763145305485d2022-12-21T18:33:11ZengShiraz University of Medical SciencesJournal of Biomedical Physics and Engineering2251-72002251-72002021-08-0111451552610.31661/jbpe.v0i0.103446458Assessment of Motor Cortex in Active, Passive and Imagery Wrist Movement using Functional MRIHamid Sharini0Shokufeh Zolghadriha1Nader Riyahi Alam2Maziar Jalalvandi3Hamid Khabiri4Hossein Arabalibeik5Mohadeseh Nadimi6PhD, Department of Medical Physics and Biomedical Engineering, School of Medicine, Kermanshah University of Medical Sciences (KUMS), Kermanshah, IranMSc, Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, IranPhD, Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, IranMSc, Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, IranPhD, Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, IranPhD, Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, IranMSc, Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, IranBackground: Functional Magnetic resonance imaging (fMRI) measures the small fluctuation of blood flow happening during task-fMRI in brain regions. Objective: This research investigated these active, imagery and passive movements in volunteers design to permit a comparison of their capabilities in activating the brain areas.Material and Methods: In this applied research, the activity of the motor cortex during the right-wrist movement was evaluated in 10 normal volunteers under active, passive, and imagery conditions. T2* weighted, three-dimensional functional images were acquired using a BOLD sensitive gradient-echo EPI (echo planar imaging) sequence with echo time (TE) of 30 ms and repetition time (TR) of 2000 ms. The functional data, which included 248 volumes per subject and condition, were acquired using the blocked design paradigm. The images were analyzed by the SPM12 toolbox, MATLAB software. Results: The findings determined a significant increase in signal intensity of the motor cortex while performing the test compared to the rest time (p < 0.05). It was also observed that the active areas in hand representation of the motor cortex are different in terms of locations and the number of voxels in different wrist directions. Moreover, the findings showed that the position of active centers in the brain is different in active, passive, and imagery conditions. Conclusion: Results confirm that primary motor cortex neurons play an essential role in the processing of complex information and are designed to control the direction of movement. It seems that the findings of this study can be applied for rehabilitation studies.https://jbpe.sums.ac.ir/article_46458_5b48143a5722f1f93261fcabab16e26c.pdffunctional mriactive movementpassive movementimaginary movementmotor cortexrehabilitationbrain-computer interfaceswrist movement |
| spellingShingle | Hamid Sharini Shokufeh Zolghadriha Nader Riyahi Alam Maziar Jalalvandi Hamid Khabiri Hossein Arabalibeik Mohadeseh Nadimi Assessment of Motor Cortex in Active, Passive and Imagery Wrist Movement using Functional MRI Journal of Biomedical Physics and Engineering functional mri active movement passive movement imaginary movement motor cortex rehabilitation brain-computer interfaces wrist movement |
| title | Assessment of Motor Cortex in Active, Passive and Imagery Wrist Movement using Functional MRI |
| title_full | Assessment of Motor Cortex in Active, Passive and Imagery Wrist Movement using Functional MRI |
| title_fullStr | Assessment of Motor Cortex in Active, Passive and Imagery Wrist Movement using Functional MRI |
| title_full_unstemmed | Assessment of Motor Cortex in Active, Passive and Imagery Wrist Movement using Functional MRI |
| title_short | Assessment of Motor Cortex in Active, Passive and Imagery Wrist Movement using Functional MRI |
| title_sort | assessment of motor cortex in active passive and imagery wrist movement using functional mri |
| topic | functional mri active movement passive movement imaginary movement motor cortex rehabilitation brain-computer interfaces wrist movement |
| url | https://jbpe.sums.ac.ir/article_46458_5b48143a5722f1f93261fcabab16e26c.pdf |
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