Microwave assisted oxidative coupling of thiols to symmetrical disulfides with tripropylammonium fluorochromate(VI) (TPAFC)
Tripropylammonium fluorochromate(VI) (TPAFC) is an efficient and novel reagent, which can be prepared easily and oxidizes thiols to the corresponding disulfides, quickly. The reactions are performed cleanly and are controlled to stop at the disulfide stage, without over-oxidation or side products. C...
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| Format: | Article |
| Language: | English |
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Chemical Society of Ethiopia
2012-12-01
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| Series: | Bulletin of the Chemical Society of Ethiopia |
| Subjects: | |
| Online Access: | http://www.ajol.info/index.php/bcse/article/view/72969 |
| _version_ | 1828530355541377024 |
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| author | Shahriare Ghammamy Mohammad Kazem Mohammadi |
| author_facet | Shahriare Ghammamy Mohammad Kazem Mohammadi |
| author_sort | Shahriare Ghammamy |
| collection | DOAJ |
| description | Tripropylammonium fluorochromate(VI) (TPAFC) is an efficient and novel reagent, which can be prepared easily and oxidizes thiols to the corresponding disulfides, quickly. The reactions are performed cleanly and are controlled to stop at the disulfide stage, without over-oxidation or side products. Coupling of thiols to their corresponding disulfides, was studied in solution at room temperature and under conditions using a minimal amount of solvent under microwave irradiation. The easy procedure, simple work-up, short reaction times, and excellent yields are other advantages of this reagent.DOI: http://dx.doi.org/10.4314/bcse.v26i1.16 |
| first_indexed | 2024-12-11T22:22:31Z |
| format | Article |
| id | doaj.art-9772d9fb845a46aa864b4cf37d7b75a5 |
| institution | Directory Open Access Journal |
| issn | 1011-3924 1726-801X |
| language | English |
| last_indexed | 2024-12-11T22:22:31Z |
| publishDate | 2012-12-01 |
| publisher | Chemical Society of Ethiopia |
| record_format | Article |
| series | Bulletin of the Chemical Society of Ethiopia |
| spelling | doaj.art-9772d9fb845a46aa864b4cf37d7b75a52022-12-22T00:48:24ZengChemical Society of EthiopiaBulletin of the Chemical Society of Ethiopia1011-39241726-801X2012-12-01261139144Microwave assisted oxidative coupling of thiols to symmetrical disulfides with tripropylammonium fluorochromate(VI) (TPAFC)Shahriare GhammamyMohammad Kazem MohammadiTripropylammonium fluorochromate(VI) (TPAFC) is an efficient and novel reagent, which can be prepared easily and oxidizes thiols to the corresponding disulfides, quickly. The reactions are performed cleanly and are controlled to stop at the disulfide stage, without over-oxidation or side products. Coupling of thiols to their corresponding disulfides, was studied in solution at room temperature and under conditions using a minimal amount of solvent under microwave irradiation. The easy procedure, simple work-up, short reaction times, and excellent yields are other advantages of this reagent.DOI: http://dx.doi.org/10.4314/bcse.v26i1.16http://www.ajol.info/index.php/bcse/article/view/72969ThiolOxidationCouplingDisulfideTripropylammonium fluorochromateMicrowave irradiation |
| spellingShingle | Shahriare Ghammamy Mohammad Kazem Mohammadi Microwave assisted oxidative coupling of thiols to symmetrical disulfides with tripropylammonium fluorochromate(VI) (TPAFC) Bulletin of the Chemical Society of Ethiopia Thiol Oxidation Coupling Disulfide Tripropylammonium fluorochromate Microwave irradiation |
| title | Microwave assisted oxidative coupling of thiols to symmetrical disulfides with tripropylammonium fluorochromate(VI) (TPAFC) |
| title_full | Microwave assisted oxidative coupling of thiols to symmetrical disulfides with tripropylammonium fluorochromate(VI) (TPAFC) |
| title_fullStr | Microwave assisted oxidative coupling of thiols to symmetrical disulfides with tripropylammonium fluorochromate(VI) (TPAFC) |
| title_full_unstemmed | Microwave assisted oxidative coupling of thiols to symmetrical disulfides with tripropylammonium fluorochromate(VI) (TPAFC) |
| title_short | Microwave assisted oxidative coupling of thiols to symmetrical disulfides with tripropylammonium fluorochromate(VI) (TPAFC) |
| title_sort | microwave assisted oxidative coupling of thiols to symmetrical disulfides with tripropylammonium fluorochromate vi tpafc |
| topic | Thiol Oxidation Coupling Disulfide Tripropylammonium fluorochromate Microwave irradiation |
| url | http://www.ajol.info/index.php/bcse/article/view/72969 |
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