Analgesic-like Activity of Essential Oils Constituents
Research on neuroactive drugs is a pharmaceutical sector of high interest and growth. The discovery of efficient drugs that can relieve pain is a subject of research in the pharmaceutical industry and academic field because pain is a symptom of many diseases. This review will summarize results on th...
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| Format: | Article |
| Language: | English |
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MDPI AG
2011-03-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/16/3/2233/ |
| _version_ | 1828215279432237056 |
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| author | Damião Pergentino de Sousa |
| author_facet | Damião Pergentino de Sousa |
| author_sort | Damião Pergentino de Sousa |
| collection | DOAJ |
| description | Research on neuroactive drugs is a pharmaceutical sector of high interest and growth. The discovery of efficient drugs that can relieve pain is a subject of research in the pharmaceutical industry and academic field because pain is a symptom of many diseases. This review will summarize results on the discovery of essential oil constituents with analgesic-like activity from the chemical and pharmacological perspectives. Overall, 43 bioactive compounds were selected in nociception models. Among them, 62.8% were monoterpenes, 18.6% sesquiterpenes and other constituents represented 18.6%. The data show the potential of this group of natural product chemicals as analgesic drugs that may be useful for therapeutic purposes. |
| first_indexed | 2024-04-12T15:18:38Z |
| format | Article |
| id | doaj.art-977415eca5fe45bd8fed9ed0f1747eb1 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-12T15:18:38Z |
| publishDate | 2011-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-977415eca5fe45bd8fed9ed0f1747eb12022-12-22T03:27:32ZengMDPI AGMolecules1420-30492011-03-011632233225210.3390/molecules16032233Analgesic-like Activity of Essential Oils ConstituentsDamião Pergentino de SousaResearch on neuroactive drugs is a pharmaceutical sector of high interest and growth. The discovery of efficient drugs that can relieve pain is a subject of research in the pharmaceutical industry and academic field because pain is a symptom of many diseases. This review will summarize results on the discovery of essential oil constituents with analgesic-like activity from the chemical and pharmacological perspectives. Overall, 43 bioactive compounds were selected in nociception models. Among them, 62.8% were monoterpenes, 18.6% sesquiterpenes and other constituents represented 18.6%. The data show the potential of this group of natural product chemicals as analgesic drugs that may be useful for therapeutic purposes.http://www.mdpi.com/1420-3049/16/3/2233/analgesicantinociceptiveessential oilsterpenesnatural products |
| spellingShingle | Damião Pergentino de Sousa Analgesic-like Activity of Essential Oils Constituents Molecules analgesic antinociceptive essential oils terpenes natural products |
| title | Analgesic-like Activity of Essential Oils Constituents |
| title_full | Analgesic-like Activity of Essential Oils Constituents |
| title_fullStr | Analgesic-like Activity of Essential Oils Constituents |
| title_full_unstemmed | Analgesic-like Activity of Essential Oils Constituents |
| title_short | Analgesic-like Activity of Essential Oils Constituents |
| title_sort | analgesic like activity of essential oils constituents |
| topic | analgesic antinociceptive essential oils terpenes natural products |
| url | http://www.mdpi.com/1420-3049/16/3/2233/ |
| work_keys_str_mv | AT damiaopergentinodesousa analgesiclikeactivityofessentialoilsconstituents |