Effect of Six Months Yoga Intervention on Metabolic Profile and Carotid Intima Media Thickness in Prediabetes

Introduction: Diabetes, the most common endocrine disorder, is projected to show a worldwide increase from 366 million people in the year 2011 to 552 million in the year 2030, out of which around 101 million is expected to be contributed by India. Moreover, the disease manifestations start in th...

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Main Authors: Neha Saboo, Sudhanshu Kacker, Jeevraj Rathore
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2021-04-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://www.jcdr.net/articles/PDF/14699/47146_CE[Ra1]_F[SK]_PF1(AG_OM)_PFA(KM)_PB(AG_KM)_PN(KM).pdf
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author Neha Saboo
Sudhanshu Kacker
Jeevraj Rathore
author_facet Neha Saboo
Sudhanshu Kacker
Jeevraj Rathore
author_sort Neha Saboo
collection DOAJ
description Introduction: Diabetes, the most common endocrine disorder, is projected to show a worldwide increase from 366 million people in the year 2011 to 552 million in the year 2030, out of which around 101 million is expected to be contributed by India. Moreover, the disease manifestations start in the early stages of diabetes and before it gets established as a full blown condition in the pre-stage called prediabetes. Aim: To highlight the importance of yoga intervention on metabolic profile and Carotid Intima Media Thickness (CIMT) in prediabetic subjects and implement it as a therapy for primary prevention of diabetes. Materials and Methods: This interventional study was done among adults aged 31-50 years in RUHS College of Medical Sciences and Associated Rukmani Devi Beni Prasad Jaipuria Hospital in Jaipur City, Rajasthan, India. A total of 250 prediabetic subjects were recruited from Jaipuria Hospital. These were divided into two groups, Study group (Group A, n=125) were engaged in yoga session and Control group (Group B, n=125) did not perform any yoga session. Written informed consent was taken from the participants in the local language. Study was conducted over a period of six months from July to December 2018. Statistical analysis was done by student’s paired t-test for intragroup comparison before applying this test the Smirnov-Kolmogorov test was conducted to confirm the normality of each parameter. Results: Yoga intervention resulted in a significant decline in blood glucose (p<0.0001), Glycated haemoglobin (p<0.01), lipid profile Cholesterol (p<0.01), Triglyceride (p<0.01), Low Density Lipoprotein (LDL) (p<0.01), High Density Lipoprotein (HDL) (p-value >0.05) and Very Low Density Lipoprotein (VLDL) (p-value >0.05), CIMT (p-value <0.05) relative to the control group. Conclusion: Yoga intervention was found to be helpful in control of metabolic profile and CIMT in prediabetes subjects. This preliminary study indicates that a yoga intervention would be a possible risk reduction option for adults at high risk for type 2 diabetes. In addition, yoga holds promise as an approach in reducing cardiometabolic risk factors, atherosclerosis and Cardiovascular (CV) events.
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spelling doaj.art-97797f58df504d4899ccf2b018d8c56b2022-12-21T21:59:48ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2021-04-01154CC01CC0510.7860/JCDR/2021/47146.14699Effect of Six Months Yoga Intervention on Metabolic Profile and Carotid Intima Media Thickness in PrediabetesNeha Saboo0Sudhanshu Kacker1Jeevraj Rathore2Assistant Professor, Department of Physiology, RUHS College of Medical Sciences, Jaipur, Rajasthan, India.Professor, Department of Physiology, RUHS College of Medical Sciences, Jaipur, Rajasthan, India.Professor, Department of Radiology, RUHS College of Medical Sciences, Jaipur, Rajasthan, India.Introduction: Diabetes, the most common endocrine disorder, is projected to show a worldwide increase from 366 million people in the year 2011 to 552 million in the year 2030, out of which around 101 million is expected to be contributed by India. Moreover, the disease manifestations start in the early stages of diabetes and before it gets established as a full blown condition in the pre-stage called prediabetes. Aim: To highlight the importance of yoga intervention on metabolic profile and Carotid Intima Media Thickness (CIMT) in prediabetic subjects and implement it as a therapy for primary prevention of diabetes. Materials and Methods: This interventional study was done among adults aged 31-50 years in RUHS College of Medical Sciences and Associated Rukmani Devi Beni Prasad Jaipuria Hospital in Jaipur City, Rajasthan, India. A total of 250 prediabetic subjects were recruited from Jaipuria Hospital. These were divided into two groups, Study group (Group A, n=125) were engaged in yoga session and Control group (Group B, n=125) did not perform any yoga session. Written informed consent was taken from the participants in the local language. Study was conducted over a period of six months from July to December 2018. Statistical analysis was done by student’s paired t-test for intragroup comparison before applying this test the Smirnov-Kolmogorov test was conducted to confirm the normality of each parameter. Results: Yoga intervention resulted in a significant decline in blood glucose (p<0.0001), Glycated haemoglobin (p<0.01), lipid profile Cholesterol (p<0.01), Triglyceride (p<0.01), Low Density Lipoprotein (LDL) (p<0.01), High Density Lipoprotein (HDL) (p-value >0.05) and Very Low Density Lipoprotein (VLDL) (p-value >0.05), CIMT (p-value <0.05) relative to the control group. Conclusion: Yoga intervention was found to be helpful in control of metabolic profile and CIMT in prediabetes subjects. This preliminary study indicates that a yoga intervention would be a possible risk reduction option for adults at high risk for type 2 diabetes. In addition, yoga holds promise as an approach in reducing cardiometabolic risk factors, atherosclerosis and Cardiovascular (CV) events.https://www.jcdr.net/articles/PDF/14699/47146_CE[Ra1]_F[SK]_PF1(AG_OM)_PFA(KM)_PB(AG_KM)_PN(KM).pdfblood glucoseglycated haemoglobinlifestyle interventionlipid profile
spellingShingle Neha Saboo
Sudhanshu Kacker
Jeevraj Rathore
Effect of Six Months Yoga Intervention on Metabolic Profile and Carotid Intima Media Thickness in Prediabetes
Journal of Clinical and Diagnostic Research
blood glucose
glycated haemoglobin
lifestyle intervention
lipid profile
title Effect of Six Months Yoga Intervention on Metabolic Profile and Carotid Intima Media Thickness in Prediabetes
title_full Effect of Six Months Yoga Intervention on Metabolic Profile and Carotid Intima Media Thickness in Prediabetes
title_fullStr Effect of Six Months Yoga Intervention on Metabolic Profile and Carotid Intima Media Thickness in Prediabetes
title_full_unstemmed Effect of Six Months Yoga Intervention on Metabolic Profile and Carotid Intima Media Thickness in Prediabetes
title_short Effect of Six Months Yoga Intervention on Metabolic Profile and Carotid Intima Media Thickness in Prediabetes
title_sort effect of six months yoga intervention on metabolic profile and carotid intima media thickness in prediabetes
topic blood glucose
glycated haemoglobin
lifestyle intervention
lipid profile
url https://www.jcdr.net/articles/PDF/14699/47146_CE[Ra1]_F[SK]_PF1(AG_OM)_PFA(KM)_PB(AG_KM)_PN(KM).pdf
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