Angiotensin-converting enzyme DD genotype in patients with primary pulmonary hypertension: increased frequency and association with preserved haemodynamics

Angiotensin-converting enzyme DD genotype in patients with primary pulmonary hypertension: increased frequency and association with preserved haemodynamics

Hypothesis/introduction A polymorphic marker within the angiotensin-converting enzyme (ACE) gene has been associated with circulating and tissue ACE activity and with a variety of forms of cardiovascular disease. Since angiotensin II (Ang II) causes pulmonary vasoconstriction and vascular and myocar...

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Main Authors: William T Abraham, Mary V Raynolds, David B Badesch, Kristine M Wynne, Bertron M Groves, Robert L Roden, Alastair D Robertson, Brian D Lowes, Lawrence S Zisman, Norbert F Voelkel, Michael R Bristow, M Benjamin Perryman
Format: Article
Language:English
Published: SAGE Publications 2003-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2003.003

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