Atypical Endometrial Hyperplasia Arising in a Cesarean Section Scar: A Mechanism of Malignant Transformation
The incidence of scar endometriosis in Cesarean sections varies between 0.03 and 0.4%. However, the recently increased rate of Cesarean sections worldwide may be causing an increase in occurrence of scar endometriosis. This report presents anatomopathological evidence of an early-stage malignant tra...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2019-04-01
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| Series: | Case Reports in Oncology |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/499760 |
| _version_ | 1818500776096432128 |
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| author | Marta Monist Dorota Lewkowicz Maciej Jóźwik Marek Gogacz Michał Bogusiewicz Tomasz Rechberger Andrzej Semczuk |
| author_facet | Marta Monist Dorota Lewkowicz Maciej Jóźwik Marek Gogacz Michał Bogusiewicz Tomasz Rechberger Andrzej Semczuk |
| author_sort | Marta Monist |
| collection | DOAJ |
| description | The incidence of scar endometriosis in Cesarean sections varies between 0.03 and 0.4%. However, the recently increased rate of Cesarean sections worldwide may be causing an increase in occurrence of scar endometriosis. This report presents anatomopathological evidence of an early-stage malignant transformation in endometriotic tissue from a post-Cesarean scar and briefly reviews possible underlying mechanisms. A 40-year-old woman with a body mass index of 42.7 was referred to the gynecological department with recurrent pain and presence of a palpable mass in her Cesarean section scar. She had undergone this procedure 7 years earlier and began experiencing discomfort and pain at the incision site 6 months postoperatively. Surgical treatment was instituted with complete removal of the lesion. Anatomopathological examination revealed endometriotic tissue intertwined with atypical endometrial hyperplasia and fibrosis. At 2 years’ follow-up, she was asymptomatic, both clinically and based on ultrasound examination. Endometriotic foci inoculated within an abdominal scar may undergo malignant transformation. Long-lasting abdominal scar endometriosis, in morbidly obese women, requires special attention from the physician. |
| first_indexed | 2024-12-10T20:47:21Z |
| format | Article |
| id | doaj.art-977e0e9ee9e14780b5b264b5434d5ab5 |
| institution | Directory Open Access Journal |
| issn | 1662-6575 |
| language | English |
| last_indexed | 2024-12-10T20:47:21Z |
| publishDate | 2019-04-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj.art-977e0e9ee9e14780b5b264b5434d5ab52022-12-22T01:34:12ZengKarger PublishersCase Reports in Oncology1662-65752019-04-0112131732110.1159/000499760499760Atypical Endometrial Hyperplasia Arising in a Cesarean Section Scar: A Mechanism of Malignant TransformationMarta MonistDorota LewkowiczMaciej JóźwikMarek GogaczMichał BogusiewiczTomasz RechbergerAndrzej SemczukThe incidence of scar endometriosis in Cesarean sections varies between 0.03 and 0.4%. However, the recently increased rate of Cesarean sections worldwide may be causing an increase in occurrence of scar endometriosis. This report presents anatomopathological evidence of an early-stage malignant transformation in endometriotic tissue from a post-Cesarean scar and briefly reviews possible underlying mechanisms. A 40-year-old woman with a body mass index of 42.7 was referred to the gynecological department with recurrent pain and presence of a palpable mass in her Cesarean section scar. She had undergone this procedure 7 years earlier and began experiencing discomfort and pain at the incision site 6 months postoperatively. Surgical treatment was instituted with complete removal of the lesion. Anatomopathological examination revealed endometriotic tissue intertwined with atypical endometrial hyperplasia and fibrosis. At 2 years’ follow-up, she was asymptomatic, both clinically and based on ultrasound examination. Endometriotic foci inoculated within an abdominal scar may undergo malignant transformation. Long-lasting abdominal scar endometriosis, in morbidly obese women, requires special attention from the physician.https://www.karger.com/Article/FullText/499760Atypical endometrial hyperplasiaCesarean sectionEndometriosisObesity |
| spellingShingle | Marta Monist Dorota Lewkowicz Maciej Jóźwik Marek Gogacz Michał Bogusiewicz Tomasz Rechberger Andrzej Semczuk Atypical Endometrial Hyperplasia Arising in a Cesarean Section Scar: A Mechanism of Malignant Transformation Case Reports in Oncology Atypical endometrial hyperplasia Cesarean section Endometriosis Obesity |
| title | Atypical Endometrial Hyperplasia Arising in a Cesarean Section Scar: A Mechanism of Malignant Transformation |
| title_full | Atypical Endometrial Hyperplasia Arising in a Cesarean Section Scar: A Mechanism of Malignant Transformation |
| title_fullStr | Atypical Endometrial Hyperplasia Arising in a Cesarean Section Scar: A Mechanism of Malignant Transformation |
| title_full_unstemmed | Atypical Endometrial Hyperplasia Arising in a Cesarean Section Scar: A Mechanism of Malignant Transformation |
| title_short | Atypical Endometrial Hyperplasia Arising in a Cesarean Section Scar: A Mechanism of Malignant Transformation |
| title_sort | atypical endometrial hyperplasia arising in a cesarean section scar a mechanism of malignant transformation |
| topic | Atypical endometrial hyperplasia Cesarean section Endometriosis Obesity |
| url | https://www.karger.com/Article/FullText/499760 |
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