The value of red cell distribution width for predicting subsequent preeclampsia

Purpose: The purpose of our study was too assess the diagnostic value of red cell distribution width and other inflammatory markers such as white blood cell count and mean platelet volume during the first trimester of gestation for predicting the subsequent development of preeclampsia.Material and M...

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Main Authors: Atalay Ekin, Cenk Gezer, Cüneyt Taner, Gökhan Tosun, Mehmet Özeren, Ulaş Solmaz
Format: Article
Language:English
Published: Cukurova University 2016-06-01
Series:Cukurova Medical Journal
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/206096
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author Atalay Ekin
Cenk Gezer
Cüneyt Taner
Gökhan Tosun
Mehmet Özeren
Ulaş Solmaz
author_facet Atalay Ekin
Cenk Gezer
Cüneyt Taner
Gökhan Tosun
Mehmet Özeren
Ulaş Solmaz
author_sort Atalay Ekin
collection DOAJ
description Purpose: The purpose of our study was too assess the diagnostic value of red cell distribution width and other inflammatory markers such as white blood cell count and mean platelet volume during the first trimester of gestation for predicting the subsequent development of preeclampsia.Material and Methods: A retrospective study was performed on 137 patients with preeclampsia and 150 normotensive pregnant women. Study group was assessed for presence of preeclampsia and the values of first trimester red cell distribution width, white blood cell count and mean platelet volume. The receiver operator curve was used to evaluate cut-off, sensitivity and specificity values.Results: The optimal cut-off points to predict preeclampsia were a white blood cell count 10200 cells/mm3 or higher with a sensitivity of 75.1% and specificity of 44.1%, a mean platelet volume 8.6fL or lower with a sensitivity of 62.5% and specificity of 64.4% and a red cell distribution width 15.3% or lower with a sensitivity of 31.2% and specificity of 79.7%.Conclusion: Regarding the association between first trimester red cell distribution width, white blood cell count and mean platelet volume, statistical analysis revealed that these markers were weak predictors of preeclampsia
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spelling doaj.art-977eb75c6504465892abed6cc7ecc7af2023-02-15T16:18:28ZengCukurova UniversityCukurova Medical Journal2602-30402016-06-0141222422848The value of red cell distribution width for predicting subsequent preeclampsiaAtalay EkinCenk GezerCüneyt TanerGökhan TosunMehmet ÖzerenUlaş SolmazPurpose: The purpose of our study was too assess the diagnostic value of red cell distribution width and other inflammatory markers such as white blood cell count and mean platelet volume during the first trimester of gestation for predicting the subsequent development of preeclampsia.Material and Methods: A retrospective study was performed on 137 patients with preeclampsia and 150 normotensive pregnant women. Study group was assessed for presence of preeclampsia and the values of first trimester red cell distribution width, white blood cell count and mean platelet volume. The receiver operator curve was used to evaluate cut-off, sensitivity and specificity values.Results: The optimal cut-off points to predict preeclampsia were a white blood cell count 10200 cells/mm3 or higher with a sensitivity of 75.1% and specificity of 44.1%, a mean platelet volume 8.6fL or lower with a sensitivity of 62.5% and specificity of 64.4% and a red cell distribution width 15.3% or lower with a sensitivity of 31.2% and specificity of 79.7%.Conclusion: Regarding the association between first trimester red cell distribution width, white blood cell count and mean platelet volume, statistical analysis revealed that these markers were weak predictors of preeclampsiahttps://dergipark.org.tr/tr/download/article-file/206096eritrosit dağılım genişliği lökosit ortalama platelet hacmi preeklampsi
spellingShingle Atalay Ekin
Cenk Gezer
Cüneyt Taner
Gökhan Tosun
Mehmet Özeren
Ulaş Solmaz
The value of red cell distribution width for predicting subsequent preeclampsia
Cukurova Medical Journal
eritrosit dağılım genişliği
lökosit
ortalama platelet hacmi
preeklampsi
title The value of red cell distribution width for predicting subsequent preeclampsia
title_full The value of red cell distribution width for predicting subsequent preeclampsia
title_fullStr The value of red cell distribution width for predicting subsequent preeclampsia
title_full_unstemmed The value of red cell distribution width for predicting subsequent preeclampsia
title_short The value of red cell distribution width for predicting subsequent preeclampsia
title_sort value of red cell distribution width for predicting subsequent preeclampsia
topic eritrosit dağılım genişliği
lökosit
ortalama platelet hacmi
preeklampsi
url https://dergipark.org.tr/tr/download/article-file/206096
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