Biomimetic properties and estimated in vivo distribution of chloroquine and hydroxy-chloroquine enantiomers
Chloroquine and hydroxy-chloroquine already established as anti-malarial and lupus drugs have recently gained renewed attention in the fight against the Covid-19 pandemic. Bio-mimetic HPLC methods have been used to measure the protein and phospholipid binding of the racemic mixtures of the drugs. Th...
Main Authors: | Klara Livia Valko, Tong Zhang |
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Format: | Article |
Language: | English |
Published: |
International Association of Physical Chemists (IAPC)
2021-01-01
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Series: | ADMET and DMPK |
Online Access: | https://www.pub.iapchem.org/ojs/index.php/admet/article/view/929 |
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