All clinically-relevant blood components transmit prion disease following a single blood transfusion: a sheep model of vCJD.

Variant CJD (vCJD) is an incurable, infectious human disease, likely arising from the consumption of BSE-contaminated meat products. Whilst the epidemic appears to be waning, there is much concern that vCJD infection may be perpetuated in humans by the transfusion of contaminated blood products. Sin...

Full description

Bibliographic Details
Main Authors: Sandra McCutcheon, Anthony Richard Alejo Blanco, E Fiona Houston, Christopher de Wolf, Boon Chin Tan, Antony Smith, Martin H Groschup, Nora Hunter, Valerie S Hornsey, Ian R MacGregor, Christopher V Prowse, Marc Turner, Jean C Manson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3157369?pdf=render