Cardiac Children Hospital Early Warning ScoreVersus the Inadequate Oxygen Delivery Index for the Detection of Early Warning Signs of Deterioration

OBJECTIVES:. To assess the utility of the Cardiac Children’s Hospital Early Warning Score (C-CHEWS) in the early detection of deterioration. DESIGN:. Single-center longitudinal pilot study. SETTING:. Pediatric cardiac ICU (PCICU), Aga Khan University. INTERVENTIONS:. C-CHEWS and Inadequate Oxygen De...

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Main Authors: Mujtaba Khalil, MBBS, Qalab Abbas, MBBS, FCPS, Mohammad Kumael Azhar, MBBS, Faiqa Binte Aamir, MBBS, Shiraz Hashmi, MBBS, MSc, Sadaqat Ali, BScN, Tahira Faiz, BScN, Mahim Akmal Malik, MD
Format: Article
Language:English
Published: Wolters Kluwer 2023-01-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000000833
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author Mujtaba Khalil, MBBS
Qalab Abbas, MBBS, FCPS
Mohammad Kumael Azhar, MBBS
Faiqa Binte Aamir, MBBS
Shiraz Hashmi, MBBS, MSc
Sadaqat Ali, BScN
Tahira Faiz, BScN
Mahim Akmal Malik, MD
author_facet Mujtaba Khalil, MBBS
Qalab Abbas, MBBS, FCPS
Mohammad Kumael Azhar, MBBS
Faiqa Binte Aamir, MBBS
Shiraz Hashmi, MBBS, MSc
Sadaqat Ali, BScN
Tahira Faiz, BScN
Mahim Akmal Malik, MD
author_sort Mujtaba Khalil, MBBS
collection DOAJ
description OBJECTIVES:. To assess the utility of the Cardiac Children’s Hospital Early Warning Score (C-CHEWS) in the early detection of deterioration. DESIGN:. Single-center longitudinal pilot study. SETTING:. Pediatric cardiac ICU (PCICU), Aga Khan University. INTERVENTIONS:. C-CHEWS and Inadequate Oxygen Delivery (IDO2) Index calculation every 2 hours. PATIENTS:. A total of 60 children (0 d to 18 yr old). MEASUREMENTS AND MAIN RESULTS:. A single-center longitudinal pilot study was conducted at PCICU. All postoperative extubated patients were assessed and scored between 0 and 11, and these scores were then correlated with the IDO2 index data available from the T3 platform. Adverse events were defined as a need for cardiopulmonary resuscitation, or reintubation, and death. A total of 920 C-CHEWS and IDO2 scores were analyzed on 60 patients during the study period. There were 36 males and 24 females, and the median age of the study population was 34 months (interquartile range, 9.0–72.0 mo). Fourteen patients (23.3%) developed adverse events; these included 9 reintubations and 5 cardiopulmonary arrests, resulting in 2 deaths. The area under the curve (AUC) for C-CHEWS scores fell in an acceptable range of 0.956 (95% CI, 0.869–0.992), suggesting an optimal accuracy for identifying early warning signs of cardiopulmonary arrest. Whereas, IDO2 showed no discriminatory power to detect the adverse events with an AUC of 0.522 (95% CI, 0.389–0.652). CONCLUSIONS:. The C-CHEWS tool provides a standardized assessment and approach to deteriorating congenital cardiac surgery patients in recognizing early postoperative deterioration.
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spelling doaj.art-9789f9bde02b4343a756c826bef7cf5a2023-02-01T06:04:44ZengWolters KluwerCritical Care Explorations2639-80282023-01-0151e083310.1097/CCE.0000000000000833202301000-00026Cardiac Children Hospital Early Warning ScoreVersus the Inadequate Oxygen Delivery Index for the Detection of Early Warning Signs of DeteriorationMujtaba Khalil, MBBS0Qalab Abbas, MBBS, FCPS1Mohammad Kumael Azhar, MBBS2Faiqa Binte Aamir, MBBS3Shiraz Hashmi, MBBS, MSc4Sadaqat Ali, BScN5Tahira Faiz, BScN6Mahim Akmal Malik, MD71 Dean’s Clinical Research Program, Aga Khan University Hospital, Karachi, Pakistan.2 Department of Pediatrics, Aga Khan University Hospital, Karachi, Pakistan.3 Medical College, Aga Khan University Hospital, Karachi, Pakistan.3 Medical College, Aga Khan University Hospital, Karachi, Pakistan.4 Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.4 Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.4 Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.4 Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.OBJECTIVES:. To assess the utility of the Cardiac Children’s Hospital Early Warning Score (C-CHEWS) in the early detection of deterioration. DESIGN:. Single-center longitudinal pilot study. SETTING:. Pediatric cardiac ICU (PCICU), Aga Khan University. INTERVENTIONS:. C-CHEWS and Inadequate Oxygen Delivery (IDO2) Index calculation every 2 hours. PATIENTS:. A total of 60 children (0 d to 18 yr old). MEASUREMENTS AND MAIN RESULTS:. A single-center longitudinal pilot study was conducted at PCICU. All postoperative extubated patients were assessed and scored between 0 and 11, and these scores were then correlated with the IDO2 index data available from the T3 platform. Adverse events were defined as a need for cardiopulmonary resuscitation, or reintubation, and death. A total of 920 C-CHEWS and IDO2 scores were analyzed on 60 patients during the study period. There were 36 males and 24 females, and the median age of the study population was 34 months (interquartile range, 9.0–72.0 mo). Fourteen patients (23.3%) developed adverse events; these included 9 reintubations and 5 cardiopulmonary arrests, resulting in 2 deaths. The area under the curve (AUC) for C-CHEWS scores fell in an acceptable range of 0.956 (95% CI, 0.869–0.992), suggesting an optimal accuracy for identifying early warning signs of cardiopulmonary arrest. Whereas, IDO2 showed no discriminatory power to detect the adverse events with an AUC of 0.522 (95% CI, 0.389–0.652). CONCLUSIONS:. The C-CHEWS tool provides a standardized assessment and approach to deteriorating congenital cardiac surgery patients in recognizing early postoperative deterioration.http://journals.lww.com/10.1097/CCE.0000000000000833
spellingShingle Mujtaba Khalil, MBBS
Qalab Abbas, MBBS, FCPS
Mohammad Kumael Azhar, MBBS
Faiqa Binte Aamir, MBBS
Shiraz Hashmi, MBBS, MSc
Sadaqat Ali, BScN
Tahira Faiz, BScN
Mahim Akmal Malik, MD
Cardiac Children Hospital Early Warning ScoreVersus the Inadequate Oxygen Delivery Index for the Detection of Early Warning Signs of Deterioration
Critical Care Explorations
title Cardiac Children Hospital Early Warning ScoreVersus the Inadequate Oxygen Delivery Index for the Detection of Early Warning Signs of Deterioration
title_full Cardiac Children Hospital Early Warning ScoreVersus the Inadequate Oxygen Delivery Index for the Detection of Early Warning Signs of Deterioration
title_fullStr Cardiac Children Hospital Early Warning ScoreVersus the Inadequate Oxygen Delivery Index for the Detection of Early Warning Signs of Deterioration
title_full_unstemmed Cardiac Children Hospital Early Warning ScoreVersus the Inadequate Oxygen Delivery Index for the Detection of Early Warning Signs of Deterioration
title_short Cardiac Children Hospital Early Warning ScoreVersus the Inadequate Oxygen Delivery Index for the Detection of Early Warning Signs of Deterioration
title_sort cardiac children hospital early warning scoreversus the inadequate oxygen delivery index for the detection of early warning signs of deterioration
url http://journals.lww.com/10.1097/CCE.0000000000000833
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