ER Stress-Induced Sphingosine-1-Phosphate Lyase Phosphorylation Potentiates the Mitochondrial Unfolded Protein Response

ER Stress-Induced Sphingosine-1-Phosphate Lyase Phosphorylation Potentiates the Mitochondrial Unfolded Protein Response

The unfolded protein response (UPR) is an elaborate signaling network that evolved to maintain proteostasis in the endoplasmic reticulum (ER) and mitochondria (mt). These organelles are functionally and physically associated, and consequently, their stress responses are often intertwined. It is uncl...

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Bibliographic Details
Main Authors: Asli D. Yildirim, Mevlut Citir, Asli E. Dogan, Zehra Veli, Zehra Yildirim, Ozlem Tufanli, Alexis Traynor-Kaplan, Carsten Schultz, Ebru Erbay
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Journal of Lipid Research
Subjects:
adaptive stress response
endoplasmic reticulum
mitochondria
inositol-requiring enzyme-1
endoribonuclease
kinase
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227522001122

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