Anal cancer debuting as cancer of unknown primary

Anal cancer usually presents with a visible or palpable tumour. In this case we describe a 54-year old man diagnosed with Cancer of Unknown Primary (CUP) with a single inguinal node as the only finding. Thorough examination failed to identify any primary tumour. The patient was treated with lymph no...

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Main Authors: Joen Sveistrup, Annika Loft, Svend Aage Engelholm
Format: Article
Language:English
Published: SAGE Publishing 2011-04-01
Series:Rare Tumors
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/rt/article/view/2197
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author Joen Sveistrup
Annika Loft
Svend Aage Engelholm
author_facet Joen Sveistrup
Annika Loft
Svend Aage Engelholm
author_sort Joen Sveistrup
collection DOAJ
description Anal cancer usually presents with a visible or palpable tumour. In this case we describe a 54-year old man diagnosed with Cancer of Unknown Primary (CUP) with a single inguinal node as the only finding. Thorough examination failed to identify any primary tumour. The patient was treated with lymph node dissection and not until nearly two years after initial diagnosis, was the primary tumour found, and the patient was diagnosed with anal cancer. The patient was treated with chemoradiotherapy and 45 months after initial diagnosis there is still no sign of relapse. This case illustrates, that anal cancer can metastasise before the primary tumour is detectable. Furthermore, it demonstrates the necessity of thorough clinical follow-up after treatment of CUP since the primary tumour was found later. Finally this is a case of a long-term survivor following treatment for metastatic inguinal lymph nodes from an initially unknown primary cancer.
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spelling doaj.art-978acb7ed88d47e1aacd11fb68ab37ff2022-12-22T02:29:36ZengSAGE PublishingRare Tumors2036-36052036-36132011-04-0132e18e1810.4081/rt.2011.e181450Anal cancer debuting as cancer of unknown primaryJoen Sveistrup0Annika Loft1Svend Aage Engelholm2Department of Radiation Oncology, Rigshospitalet, Copenhagen, DenmarkPET and Cyclotron Unit, Department of Clinical Physiology and Nuclear Medicine, Centre of Diagnostic Investigations, Rigshospitalet, Copenhagen, DenmarkDepartment of Radiation Oncology, RigshospitaletAnal cancer usually presents with a visible or palpable tumour. In this case we describe a 54-year old man diagnosed with Cancer of Unknown Primary (CUP) with a single inguinal node as the only finding. Thorough examination failed to identify any primary tumour. The patient was treated with lymph node dissection and not until nearly two years after initial diagnosis, was the primary tumour found, and the patient was diagnosed with anal cancer. The patient was treated with chemoradiotherapy and 45 months after initial diagnosis there is still no sign of relapse. This case illustrates, that anal cancer can metastasise before the primary tumour is detectable. Furthermore, it demonstrates the necessity of thorough clinical follow-up after treatment of CUP since the primary tumour was found later. Finally this is a case of a long-term survivor following treatment for metastatic inguinal lymph nodes from an initially unknown primary cancer.http://www.pagepress.org/journals/index.php/rt/article/view/2197Anal CancerCarcinoma of Unknown Primary (CUP)Metastatic Inguinal Lymph Nodes
spellingShingle Joen Sveistrup
Annika Loft
Svend Aage Engelholm
Anal cancer debuting as cancer of unknown primary
Rare Tumors
Anal Cancer
Carcinoma of Unknown Primary (CUP)
Metastatic Inguinal Lymph Nodes
title Anal cancer debuting as cancer of unknown primary
title_full Anal cancer debuting as cancer of unknown primary
title_fullStr Anal cancer debuting as cancer of unknown primary
title_full_unstemmed Anal cancer debuting as cancer of unknown primary
title_short Anal cancer debuting as cancer of unknown primary
title_sort anal cancer debuting as cancer of unknown primary
topic Anal Cancer
Carcinoma of Unknown Primary (CUP)
Metastatic Inguinal Lymph Nodes
url http://www.pagepress.org/journals/index.php/rt/article/view/2197
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