Toxoplasma gondii dense granule protein 3 promotes endoplasmic reticulum stress-induced apoptosis by activating the PERK pathway

Toxoplasma gondii dense granule protein 3 promotes endoplasmic reticulum stress-induced apoptosis by activating the PERK pathway

Abstract Background Toxoplasma gondii is a neurotropic single-celled parasite that can infect mammals, including humans. Central nervous system infection with T. gondii infection can lead to Toxoplasma encephalitis. Toxoplasma infection can cause endoplasmic reticulum (ER) stress and unfolded protei...

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Bibliographic Details
Main Authors: Cudjoe Obed, Minmin Wu, Ying Chen, Ran An, Haijian Cai, Qingli Luo, Li Yu, Jie Wang, Fang Liu, Jilong Shen, Jian Du
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Parasites & Vectors
Subjects:
Toxoplasma gondii
GRA3
Endoplasmic reticulum
ER stress
UPR
Apoptosis
Online Access:https://doi.org/10.1186/s13071-022-05394-5

Internet

https://doi.org/10.1186/s13071-022-05394-5

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