A Sourcing Strategy for Active Pharmaceutical Ingredients (APIs)
We describe the development over the past decade of a sourcing strategy within the Roche group for active pharmaceutical ingredients and the intermediates used in their manufacture. The roles of certain production sites have been modified in the light of this strategy. Before sourcing deci...
| Main Authors: | , , |
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| Format: | Article |
| Language: | deu |
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Swiss Chemical Society
1998-06-01
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| Series: | CHIMIA |
| Online Access: | https://chimia.ch/chimia/article/view/3004 |
| _version_ | 1818294399458607104 |
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| author | George M. Clarke K. Peter Schnurrenberger Bernhard Scholl |
| author_facet | George M. Clarke K. Peter Schnurrenberger Bernhard Scholl |
| author_sort | George M. Clarke |
| collection | DOAJ |
| description |
We describe the development over the past decade of a sourcing strategy within the Roche group for active pharmaceutical ingredients and the intermediates used in their manufacture. The roles of certain production sites have been modified in the light of this strategy. Before
sourcing decisions are taken, criteria including life-cycle phase of the product, whether the step under review comes early or late in the synthesis, protection of proprietary know-how, quantities needed, speed, available capacity and full production costs are systematically evaluated on a
case-by-case basis. For each sourcing decision, different scenarios are compared, in particular that of in-house vs. external production. In future, we envisage intensified competition both among Contract Manufacturing Organisations (CMOs) for business from large pharma concerns and
among the large pharma concerns themselves for the capacity available from the CMOs. In consequence, the large pharma concerns will have to continually adapt their sourcing strategies to the changing environment and will have to have available flexible production plants and organisations if
they wish to maintain a viable in-house alternative to contract manufacture.
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| first_indexed | 2024-12-13T03:31:08Z |
| format | Article |
| id | doaj.art-978cdff64fc24220a41c1ed1b2a3d033 |
| institution | Directory Open Access Journal |
| issn | 0009-4293 2673-2424 |
| language | deu |
| last_indexed | 2024-12-13T03:31:08Z |
| publishDate | 1998-06-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj.art-978cdff64fc24220a41c1ed1b2a3d0332022-12-22T00:01:09ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24241998-06-01526A Sourcing Strategy for Active Pharmaceutical Ingredients (APIs)George M. ClarkeK. Peter SchnurrenbergerBernhard Scholl We describe the development over the past decade of a sourcing strategy within the Roche group for active pharmaceutical ingredients and the intermediates used in their manufacture. The roles of certain production sites have been modified in the light of this strategy. Before sourcing decisions are taken, criteria including life-cycle phase of the product, whether the step under review comes early or late in the synthesis, protection of proprietary know-how, quantities needed, speed, available capacity and full production costs are systematically evaluated on a case-by-case basis. For each sourcing decision, different scenarios are compared, in particular that of in-house vs. external production. In future, we envisage intensified competition both among Contract Manufacturing Organisations (CMOs) for business from large pharma concerns and among the large pharma concerns themselves for the capacity available from the CMOs. In consequence, the large pharma concerns will have to continually adapt their sourcing strategies to the changing environment and will have to have available flexible production plants and organisations if they wish to maintain a viable in-house alternative to contract manufacture. https://chimia.ch/chimia/article/view/3004 |
| spellingShingle | George M. Clarke K. Peter Schnurrenberger Bernhard Scholl A Sourcing Strategy for Active Pharmaceutical Ingredients (APIs) CHIMIA |
| title | A Sourcing Strategy for Active Pharmaceutical Ingredients (APIs) |
| title_full | A Sourcing Strategy for Active Pharmaceutical Ingredients (APIs) |
| title_fullStr | A Sourcing Strategy for Active Pharmaceutical Ingredients (APIs) |
| title_full_unstemmed | A Sourcing Strategy for Active Pharmaceutical Ingredients (APIs) |
| title_short | A Sourcing Strategy for Active Pharmaceutical Ingredients (APIs) |
| title_sort | sourcing strategy for active pharmaceutical ingredients apis |
| url | https://chimia.ch/chimia/article/view/3004 |
| work_keys_str_mv | AT georgemclarke asourcingstrategyforactivepharmaceuticalingredientsapis AT kpeterschnurrenberger asourcingstrategyforactivepharmaceuticalingredientsapis AT bernhardscholl asourcingstrategyforactivepharmaceuticalingredientsapis AT georgemclarke sourcingstrategyforactivepharmaceuticalingredientsapis AT kpeterschnurrenberger sourcingstrategyforactivepharmaceuticalingredientsapis AT bernhardscholl sourcingstrategyforactivepharmaceuticalingredientsapis |