A study of association of ankle–brachial Index with cardiovascular risk factors in type 2 diabetes mellitus
Background: Ankle–Brachial Index (ABI) has a proven role in the baseline assessment of the individuals who are at a risk of cardiovascular diseases. Sparse data are available regarding the association of cardiovascular risk factors in type 2 diabetes mellitus (T2DM) and ABI from India. Material and...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Journal of Clinical and Scientific Research |
| Subjects: | |
| Online Access: | http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2019;volume=8;issue=4;spage=177;epage=183;aulast=Sridhar |
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| author | Chivukula Sridhar Shubha Seshadri Vaddera Sameeraja |
| author_facet | Chivukula Sridhar Shubha Seshadri Vaddera Sameeraja |
| author_sort | Chivukula Sridhar |
| collection | DOAJ |
| description | Background: Ankle–Brachial Index (ABI) has a proven role in the baseline assessment of the individuals who are at a risk of cardiovascular diseases. Sparse data are available regarding the association of cardiovascular risk factors in type 2 diabetes mellitus (T2DM) and ABI from India.
Material and Methods: A cross-sectional study was conducted at a tertiary teaching hospital in South India among patients with T2DM during the period October 2014–June 2016. ABI was measured using vascular Doppler-sphygmomanometer. Independent cardiovascular risk factors were assessed and their association with ABI was studied.
Results: ABI was negatively correlated to cardiovascular risk factors such as age, body mass index, duration of T2DM, duration of hypertension and systolic blood pressure (SBP) and diastolic blood pressure (DBP) in the entire study population as well as in both genders separately. Among females, a statistically significant association of low ABI (<0.9) was observed with SBP and duration of hypertension only, whereas, in males, SBP, DBP and duration of T2DM were significantly associated with low ABI. Of note, among the individuals with proven coronary artery disease (CAD), statistically significant association with low ABI was also observed.
Conclusions: In our study, low ABI has been observed with increasing age, obesity, high systolic and DBPs, increasing the duration of diabetes and hypertension, however, with a distinctive statistically significant association in males and females. Among the individuals with documented CAD, a significant proportion had a low ABI. |
| first_indexed | 2024-04-13T05:34:06Z |
| format | Article |
| id | doaj.art-978fc8f5078e4641ac23097e46dd79a6 |
| institution | Directory Open Access Journal |
| issn | 2277-5706 2277-8357 |
| language | English |
| last_indexed | 2024-04-13T05:34:06Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Clinical and Scientific Research |
| spelling | doaj.art-978fc8f5078e4641ac23097e46dd79a62022-12-22T03:00:20ZengWolters Kluwer Medknow PublicationsJournal of Clinical and Scientific Research2277-57062277-83572019-01-018417718310.4103/JCSR.JCSR_45_19A study of association of ankle–brachial Index with cardiovascular risk factors in type 2 diabetes mellitusChivukula SridharShubha SeshadriVaddera SameerajaBackground: Ankle–Brachial Index (ABI) has a proven role in the baseline assessment of the individuals who are at a risk of cardiovascular diseases. Sparse data are available regarding the association of cardiovascular risk factors in type 2 diabetes mellitus (T2DM) and ABI from India. Material and Methods: A cross-sectional study was conducted at a tertiary teaching hospital in South India among patients with T2DM during the period October 2014–June 2016. ABI was measured using vascular Doppler-sphygmomanometer. Independent cardiovascular risk factors were assessed and their association with ABI was studied. Results: ABI was negatively correlated to cardiovascular risk factors such as age, body mass index, duration of T2DM, duration of hypertension and systolic blood pressure (SBP) and diastolic blood pressure (DBP) in the entire study population as well as in both genders separately. Among females, a statistically significant association of low ABI (<0.9) was observed with SBP and duration of hypertension only, whereas, in males, SBP, DBP and duration of T2DM were significantly associated with low ABI. Of note, among the individuals with proven coronary artery disease (CAD), statistically significant association with low ABI was also observed. Conclusions: In our study, low ABI has been observed with increasing age, obesity, high systolic and DBPs, increasing the duration of diabetes and hypertension, however, with a distinctive statistically significant association in males and females. Among the individuals with documented CAD, a significant proportion had a low ABI.http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2019;volume=8;issue=4;spage=177;epage=183;aulast=Sridharankle–brachial indexcardiovascularrisk factorstype 2 diabetes mellitus |
| spellingShingle | Chivukula Sridhar Shubha Seshadri Vaddera Sameeraja A study of association of ankle–brachial Index with cardiovascular risk factors in type 2 diabetes mellitus Journal of Clinical and Scientific Research ankle–brachial index cardiovascular risk factors type 2 diabetes mellitus |
| title | A study of association of ankle–brachial Index with cardiovascular risk factors in type 2 diabetes mellitus |
| title_full | A study of association of ankle–brachial Index with cardiovascular risk factors in type 2 diabetes mellitus |
| title_fullStr | A study of association of ankle–brachial Index with cardiovascular risk factors in type 2 diabetes mellitus |
| title_full_unstemmed | A study of association of ankle–brachial Index with cardiovascular risk factors in type 2 diabetes mellitus |
| title_short | A study of association of ankle–brachial Index with cardiovascular risk factors in type 2 diabetes mellitus |
| title_sort | study of association of ankle brachial index with cardiovascular risk factors in type 2 diabetes mellitus |
| topic | ankle–brachial index cardiovascular risk factors type 2 diabetes mellitus |
| url | http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2019;volume=8;issue=4;spage=177;epage=183;aulast=Sridhar |
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