Thyrotoxicosis associated with severe hypoalbuminemia and hyperbilirubinemia

Thyrotoxicosis is a known cause of nonspecific abnormalities in liver function tests: most commonly mild elevations in serum bilirubin and liver enzymes, and rarely decreases in serum albumin levels. We report a case of severe hyperbilirubinemia and hypoalbuminemia secondary to thyrotoxicosis in a 6...

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Main Authors: Mert Evlice, Zekeriya Aksoz
Format: Article
Language:English
Published: SpringerOpen 2017-01-01
Series:The Egyptian Journal of Internal Medicine
Subjects:
Online Access:http://www.esim.eg.net/article.asp?issn=1110-7782;year=2017;volume=29;issue=4;spage=196;epage=198;aulast=Evlice
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author Mert Evlice
Zekeriya Aksoz
author_facet Mert Evlice
Zekeriya Aksoz
author_sort Mert Evlice
collection DOAJ
description Thyrotoxicosis is a known cause of nonspecific abnormalities in liver function tests: most commonly mild elevations in serum bilirubin and liver enzymes, and rarely decreases in serum albumin levels. We report a case of severe hyperbilirubinemia and hypoalbuminemia secondary to thyrotoxicosis in a 64-year-old woman who presented to our emergency department with complaints of jaundice, pruritis, and chronic diarrhea. In our case, the symptoms and signs of various abnormalities in liver function tests such as serum albumin and bilirubin normalized after euthyroid state. We think that these findings are related to thyroid dysfunction. Every hyperbilirubinemia and hypoalbuminemia, which can be seen in many serious diseases, may unexpectedly appear in the long-term progression of thyrotoxicosis. Whether thyrotoxicosis is present in patients with hyperbilirubinemia and hypoalbuminemia should be evaluated.
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spelling doaj.art-979444c2c8fa4427890facf31d92d4832022-12-22T00:45:08ZengSpringerOpenThe Egyptian Journal of Internal Medicine1110-77822090-90982017-01-0129419619810.4103/ejim.ejim_7_17Thyrotoxicosis associated with severe hypoalbuminemia and hyperbilirubinemiaMert EvliceZekeriya AksozThyrotoxicosis is a known cause of nonspecific abnormalities in liver function tests: most commonly mild elevations in serum bilirubin and liver enzymes, and rarely decreases in serum albumin levels. We report a case of severe hyperbilirubinemia and hypoalbuminemia secondary to thyrotoxicosis in a 64-year-old woman who presented to our emergency department with complaints of jaundice, pruritis, and chronic diarrhea. In our case, the symptoms and signs of various abnormalities in liver function tests such as serum albumin and bilirubin normalized after euthyroid state. We think that these findings are related to thyroid dysfunction. Every hyperbilirubinemia and hypoalbuminemia, which can be seen in many serious diseases, may unexpectedly appear in the long-term progression of thyrotoxicosis. Whether thyrotoxicosis is present in patients with hyperbilirubinemia and hypoalbuminemia should be evaluated.http://www.esim.eg.net/article.asp?issn=1110-7782;year=2017;volume=29;issue=4;spage=196;epage=198;aulast=Evlicecholestasishyperbilirubinemiahyperthyroidismhypoalbuminemiajaundice
spellingShingle Mert Evlice
Zekeriya Aksoz
Thyrotoxicosis associated with severe hypoalbuminemia and hyperbilirubinemia
The Egyptian Journal of Internal Medicine
cholestasis
hyperbilirubinemia
hyperthyroidism
hypoalbuminemia
jaundice
title Thyrotoxicosis associated with severe hypoalbuminemia and hyperbilirubinemia
title_full Thyrotoxicosis associated with severe hypoalbuminemia and hyperbilirubinemia
title_fullStr Thyrotoxicosis associated with severe hypoalbuminemia and hyperbilirubinemia
title_full_unstemmed Thyrotoxicosis associated with severe hypoalbuminemia and hyperbilirubinemia
title_short Thyrotoxicosis associated with severe hypoalbuminemia and hyperbilirubinemia
title_sort thyrotoxicosis associated with severe hypoalbuminemia and hyperbilirubinemia
topic cholestasis
hyperbilirubinemia
hyperthyroidism
hypoalbuminemia
jaundice
url http://www.esim.eg.net/article.asp?issn=1110-7782;year=2017;volume=29;issue=4;spage=196;epage=198;aulast=Evlice
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AT zekeriyaaksoz thyrotoxicosisassociatedwithseverehypoalbuminemiaandhyperbilirubinemia