The role of hesperidin as a cardioprotective strategy against doxorubicin-induced cardiotoxicity: The antioxidant, anti-inflammatory, antiapoptotic, and cytoprotective potentials

The role of hesperidin as a cardioprotective strategy against doxorubicin-induced cardiotoxicity: The antioxidant, anti-inflammatory, antiapoptotic, and cytoprotective potentials

Background: Doxorubicin (DOX), an anthracycline antibiotic, is a powerful chemotherapeutic agent effective against multiple types of cancer, particularly lung, breast, bladder and hematologic neoplasia (lymphomas and leukemia). However, its therapeutic usage is restricted by its known cardiotoxicit...

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Bibliographic Details
Main Authors: Fawiziah K. Alharbi, Zafer S. Alshehri, Faez F. Alshehri, Sharif A. Alhajlah, Hesham A. Khalifa, Naief Dahran, Wael A.M. Ghonimi
Format: Article
Language:English
Published: Tripoli University 2023-12-01
Series:Open Veterinary Journal
Subjects:
doxorubicin
hesperidin
cardioprotective
cardiotoxicity
oxidative damage
Online Access:https://www.openveterinaryjournal.com/?mno=175261

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