An alternative hepatosafe treatment in leprosy
Leprosy complicated by hepatitis is one condition wherein the usual multidrug therapy cannot be used and alternate regimens are required. The World Health Organization and the Indian Association of Leprologists have recommended an alternative combination therapy of clarithromycin, ofloxacin, and clo...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Indian Journal of Drugs in Dermatology |
| Subjects: | |
| Online Access: | http://www.ijdd.in/article.asp?issn=2455-3972;year=2016;volume=2;issue=1;spage=33;epage=36;aulast=Bhide |
| _version_ | 1798043703029268480 |
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| author | Anuradha Ashok Bhide Usha N Khemani Ratnakar R Kamath Varsha Vaidyanathan Abhishek P Ponathil Mahendra M Kura |
| author_facet | Anuradha Ashok Bhide Usha N Khemani Ratnakar R Kamath Varsha Vaidyanathan Abhishek P Ponathil Mahendra M Kura |
| author_sort | Anuradha Ashok Bhide |
| collection | DOAJ |
| description | Leprosy complicated by hepatitis is one condition wherein the usual multidrug therapy cannot be used and alternate regimens are required. The World Health Organization and the Indian Association of Leprologists have recommended an alternative combination therapy of clarithromycin, ofloxacin, and clofazimine to be prescribed in such cases. However, in some cases, this combination therapy may fail to control or worsen the hepatitis. One such case of leprosy, complicated by hepatitis, who did not tolerate the recommended hepatosafe regimen was successfully treated with monthly rifampicin, ofloxacin, and minocycline, and is hence reported. |
| first_indexed | 2024-04-11T22:52:48Z |
| format | Article |
| id | doaj.art-9797807522244972bd1dfcf92197ed04 |
| institution | Directory Open Access Journal |
| issn | 2455-3972 2455-3972 |
| language | English |
| last_indexed | 2024-04-11T22:52:48Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Drugs in Dermatology |
| spelling | doaj.art-9797807522244972bd1dfcf92197ed042022-12-22T03:58:32ZengWolters Kluwer Medknow PublicationsIndian Journal of Drugs in Dermatology2455-39722455-39722016-01-0121333610.4103/2455-3972.184086An alternative hepatosafe treatment in leprosyAnuradha Ashok BhideUsha N KhemaniRatnakar R KamathVarsha VaidyanathanAbhishek P PonathilMahendra M KuraLeprosy complicated by hepatitis is one condition wherein the usual multidrug therapy cannot be used and alternate regimens are required. The World Health Organization and the Indian Association of Leprologists have recommended an alternative combination therapy of clarithromycin, ofloxacin, and clofazimine to be prescribed in such cases. However, in some cases, this combination therapy may fail to control or worsen the hepatitis. One such case of leprosy, complicated by hepatitis, who did not tolerate the recommended hepatosafe regimen was successfully treated with monthly rifampicin, ofloxacin, and minocycline, and is hence reported.http://www.ijdd.in/article.asp?issn=2455-3972;year=2016;volume=2;issue=1;spage=33;epage=36;aulast=BhideAlternative hepatosafe treatmentleprosyminocyclineofloxacinrifampicin |
| spellingShingle | Anuradha Ashok Bhide Usha N Khemani Ratnakar R Kamath Varsha Vaidyanathan Abhishek P Ponathil Mahendra M Kura An alternative hepatosafe treatment in leprosy Indian Journal of Drugs in Dermatology Alternative hepatosafe treatment leprosy minocycline ofloxacin rifampicin |
| title | An alternative hepatosafe treatment in leprosy |
| title_full | An alternative hepatosafe treatment in leprosy |
| title_fullStr | An alternative hepatosafe treatment in leprosy |
| title_full_unstemmed | An alternative hepatosafe treatment in leprosy |
| title_short | An alternative hepatosafe treatment in leprosy |
| title_sort | alternative hepatosafe treatment in leprosy |
| topic | Alternative hepatosafe treatment leprosy minocycline ofloxacin rifampicin |
| url | http://www.ijdd.in/article.asp?issn=2455-3972;year=2016;volume=2;issue=1;spage=33;epage=36;aulast=Bhide |
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