GASTRIC CANCER: MOLECULAR AND GENETIC DATA (LITERATURE REVIEW)
In the review a data about molecular and genetic aspects of different morphological variants of gastric cancer in population and family studies are generalized. Data about multiple genetic and epigenetic damages in oncogenes, tumor suppressor genes, cell cycle regulators, adhesion molecules, DNA rep...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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Russian Academy of Sciences, Tomsk National Research Medical Center
2016-02-01
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| Series: | Сибирский онкологический журнал |
| Subjects: | |
| Online Access: | https://www.siboncoj.ru/jour/article/view/33 |
| _version_ | 1797875943808696320 |
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| author | A. V. Belkovets O. V. Reschetnikov S. A. Kurilovich V. N. Maksimov |
| author_facet | A. V. Belkovets O. V. Reschetnikov S. A. Kurilovich V. N. Maksimov |
| author_sort | A. V. Belkovets |
| collection | DOAJ |
| description | In the review a data about molecular and genetic aspects of different morphological variants of gastric cancer in population and family studies are generalized. Data about multiple genetic and epigenetic damages in oncogenes, tumor suppressor genes, cell cycle regulators, adhesion molecules, DNA repair genes as well as genetic instability and telomerase activation involved in the multistep process of carcinogenesis and making a contribution to uncontrolled growth and ability to form metastases are included in the review. In article possibilities of use of specific molecular markers for early GC diagnostics are discussed. |
| first_indexed | 2024-04-10T01:55:32Z |
| format | Article |
| id | doaj.art-9797c8216dbd4cf7b68585a68804d347 |
| institution | Directory Open Access Journal |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| last_indexed | 2024-04-10T01:55:32Z |
| publishDate | 2016-02-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj.art-9797c8216dbd4cf7b68585a68804d3472023-03-13T09:05:46ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682016-02-0102566433GASTRIC CANCER: MOLECULAR AND GENETIC DATA (LITERATURE REVIEW)A. V. Belkovets0O. V. Reschetnikov1S. A. Kurilovich2V. N. Maksimov3ФГБУ «НИИ терапии и профилактической медицины» СО РАМН, г. НовосибирскФГБУ «НИИ терапии и профилактической медицины» СО РАМН, г. НовосибирскФГБУ «НИИ терапии и профилактической медицины» СО РАМН, г. Новосибирск ГБОУ ВПО «Новосибирский государственный медицинский университет», г. НовосибирсФГБУ «НИИ терапии и профилактической медицины» СО РАМН, г. НовосибирскIn the review a data about molecular and genetic aspects of different morphological variants of gastric cancer in population and family studies are generalized. Data about multiple genetic and epigenetic damages in oncogenes, tumor suppressor genes, cell cycle regulators, adhesion molecules, DNA repair genes as well as genetic instability and telomerase activation involved in the multistep process of carcinogenesis and making a contribution to uncontrolled growth and ability to form metastases are included in the review. In article possibilities of use of specific molecular markers for early GC diagnostics are discussed.https://www.siboncoj.ru/jour/article/view/33рак желудкагенетическая предрасположенностьмутации геновдиагностика |
| spellingShingle | A. V. Belkovets O. V. Reschetnikov S. A. Kurilovich V. N. Maksimov GASTRIC CANCER: MOLECULAR AND GENETIC DATA (LITERATURE REVIEW) Сибирский онкологический журнал рак желудка генетическая предрасположенность мутации генов диагностика |
| title | GASTRIC CANCER: MOLECULAR AND GENETIC DATA (LITERATURE REVIEW) |
| title_full | GASTRIC CANCER: MOLECULAR AND GENETIC DATA (LITERATURE REVIEW) |
| title_fullStr | GASTRIC CANCER: MOLECULAR AND GENETIC DATA (LITERATURE REVIEW) |
| title_full_unstemmed | GASTRIC CANCER: MOLECULAR AND GENETIC DATA (LITERATURE REVIEW) |
| title_short | GASTRIC CANCER: MOLECULAR AND GENETIC DATA (LITERATURE REVIEW) |
| title_sort | gastric cancer molecular and genetic data literature review |
| topic | рак желудка генетическая предрасположенность мутации генов диагностика |
| url | https://www.siboncoj.ru/jour/article/view/33 |
| work_keys_str_mv | AT avbelkovets gastriccancermolecularandgeneticdataliteraturereview AT ovreschetnikov gastriccancermolecularandgeneticdataliteraturereview AT sakurilovich gastriccancermolecularandgeneticdataliteraturereview AT vnmaksimov gastriccancermolecularandgeneticdataliteraturereview |