Predictor parameters for poor prognosis in patients with sudden sensorineural hearing loss: fibrinogen to albumin ratio vs C-reactive protein to albumin ratio
Introduction: Prognosis of sudden sensorineural hearing loss may be predicted using several parameters of laboratory blood analysis. Objective: To identify and investigate the most significant indicator parameters related to the poor prognosis of sudden sensorineural hearing loss. Methods: Eighty-ei...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-07-01
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| Series: | Brazilian Journal of Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1808869420301099 |
| _version_ | 1818576575409422336 |
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| author | Serkan Cayir Serkan Kayabasi Omer Hizli |
| author_facet | Serkan Cayir Serkan Kayabasi Omer Hizli |
| author_sort | Serkan Cayir |
| collection | DOAJ |
| description | Introduction: Prognosis of sudden sensorineural hearing loss may be predicted using several parameters of laboratory blood analysis. Objective: To identify and investigate the most significant indicator parameters related to the poor prognosis of sudden sensorineural hearing loss. Methods: Eighty-eight patients were included, and three groups were constituted: non-recovery group with14 patients, recovery group with 33 patients and control group with 41 individuals. We compared fibrinogen-to-albumin ratio, C-reactive protein-to-albumin ratio, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, white blood cell and hemoglobin of the groups. Then, we investigated the most significant indicator parameters related to the poor prognosis of sudden hearing loss. Results: The mean hemoglobin, mean platelet-lymphocyte ratio and median white blood cell values did not significantly differ among three groups (p = 0.36, p = 0.86 and p = 0.79, respectively). A significant difference of median fibrinogen-albumin ratio, C-reactive protein-albumin ratio, neutrophil-to-lymphocyte ratio was evident among three groups (p < 0.001, p = 0.003 and p = 0.002, respectively). Median fibrinogen-albumin ratio, C-reactive protein-albumin ratio and neutrophil-to-lymphocyte ratio values were significantly greater in the non-recovery group, compared with the controls (p < 0.001, p = 0.003 and p = 0.005, respectively). Median fibrinogen-to-albumin ratio, C-reactive protein-to-albumin ratio and neutrophil-to-lymphocyte ratio were significantly greater in the recovery group, compared with the controls (p < 0.001, p = 0.013 and p = 0.005, respectively). Moreover, the median fibrinogen-albumin ratio was significantly greater in the non-recovery group compared with the recovery group (p = 0.017). However, no statistically significant difference of median C-reactive protein-albumin ratio, neutrophil-to-lymphocyte was evident between the non-recovery and recovery groups (p = 0.15). Conclusion: Increased levels of fibrinogen-albumin ratio may be predictive for poor prognosis in patients with sudden sensorineural hearing loss. |
| first_indexed | 2024-12-16T06:16:12Z |
| format | Article |
| id | doaj.art-9797d303200a4c3eb87f910a23eb9cc3 |
| institution | Directory Open Access Journal |
| issn | 1808-8694 |
| language | English |
| last_indexed | 2024-12-16T06:16:12Z |
| publishDate | 2021-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Otorhinolaryngology |
| spelling | doaj.art-9797d303200a4c3eb87f910a23eb9cc32022-12-21T22:41:15ZengElsevierBrazilian Journal of Otorhinolaryngology1808-86942021-07-01874457461Predictor parameters for poor prognosis in patients with sudden sensorineural hearing loss: fibrinogen to albumin ratio vs C-reactive protein to albumin ratioSerkan Cayir0Serkan Kayabasi1Omer Hizli2Aksaray University, Aksaray Education and Research Hospital, Department of ENT, Aksaray, Turkey; Corresponding author.Aksaray University, Faculty of Medicine, Department of ENT, Aksaray, TurkeyGiresun University, Prof Dr. A. Ilhan Ozdemir Education and Research Hospital, Department of ENT, Giresun, TurkeyIntroduction: Prognosis of sudden sensorineural hearing loss may be predicted using several parameters of laboratory blood analysis. Objective: To identify and investigate the most significant indicator parameters related to the poor prognosis of sudden sensorineural hearing loss. Methods: Eighty-eight patients were included, and three groups were constituted: non-recovery group with14 patients, recovery group with 33 patients and control group with 41 individuals. We compared fibrinogen-to-albumin ratio, C-reactive protein-to-albumin ratio, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, white blood cell and hemoglobin of the groups. Then, we investigated the most significant indicator parameters related to the poor prognosis of sudden hearing loss. Results: The mean hemoglobin, mean platelet-lymphocyte ratio and median white blood cell values did not significantly differ among three groups (p = 0.36, p = 0.86 and p = 0.79, respectively). A significant difference of median fibrinogen-albumin ratio, C-reactive protein-albumin ratio, neutrophil-to-lymphocyte ratio was evident among three groups (p < 0.001, p = 0.003 and p = 0.002, respectively). Median fibrinogen-albumin ratio, C-reactive protein-albumin ratio and neutrophil-to-lymphocyte ratio values were significantly greater in the non-recovery group, compared with the controls (p < 0.001, p = 0.003 and p = 0.005, respectively). Median fibrinogen-to-albumin ratio, C-reactive protein-to-albumin ratio and neutrophil-to-lymphocyte ratio were significantly greater in the recovery group, compared with the controls (p < 0.001, p = 0.013 and p = 0.005, respectively). Moreover, the median fibrinogen-albumin ratio was significantly greater in the non-recovery group compared with the recovery group (p = 0.017). However, no statistically significant difference of median C-reactive protein-albumin ratio, neutrophil-to-lymphocyte was evident between the non-recovery and recovery groups (p = 0.15). Conclusion: Increased levels of fibrinogen-albumin ratio may be predictive for poor prognosis in patients with sudden sensorineural hearing loss.http://www.sciencedirect.com/science/article/pii/S1808869420301099Sudden sensorineural hearing lossFibrinogenC-reactive proteinAlbumin |
| spellingShingle | Serkan Cayir Serkan Kayabasi Omer Hizli Predictor parameters for poor prognosis in patients with sudden sensorineural hearing loss: fibrinogen to albumin ratio vs C-reactive protein to albumin ratio Brazilian Journal of Otorhinolaryngology Sudden sensorineural hearing loss Fibrinogen C-reactive protein Albumin |
| title | Predictor parameters for poor prognosis in patients with sudden sensorineural hearing loss: fibrinogen to albumin ratio vs C-reactive protein to albumin ratio |
| title_full | Predictor parameters for poor prognosis in patients with sudden sensorineural hearing loss: fibrinogen to albumin ratio vs C-reactive protein to albumin ratio |
| title_fullStr | Predictor parameters for poor prognosis in patients with sudden sensorineural hearing loss: fibrinogen to albumin ratio vs C-reactive protein to albumin ratio |
| title_full_unstemmed | Predictor parameters for poor prognosis in patients with sudden sensorineural hearing loss: fibrinogen to albumin ratio vs C-reactive protein to albumin ratio |
| title_short | Predictor parameters for poor prognosis in patients with sudden sensorineural hearing loss: fibrinogen to albumin ratio vs C-reactive protein to albumin ratio |
| title_sort | predictor parameters for poor prognosis in patients with sudden sensorineural hearing loss fibrinogen to albumin ratio vs c reactive protein to albumin ratio |
| topic | Sudden sensorineural hearing loss Fibrinogen C-reactive protein Albumin |
| url | http://www.sciencedirect.com/science/article/pii/S1808869420301099 |
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