Bone marrow mesenchymal stem cells derived from juvenile macaques reversed ovarian ageing in elderly macaques

Bone marrow mesenchymal stem cells derived from juvenile macaques reversed ovarian ageing in elderly macaques

Abstract Background Female sex hormone secretion and reproductive ability decrease with ageing. Bone marrow mesenchymal stem cells (BMMSCs) have been postulated to play a key role in treating ovarian ageing. Methods We used macaque ovarian ageing models to observe the structural and functional chang...

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Main Authors: Chuan Tian, Jie He, Yuanyuan An, Zailing Yang, Donghai Yan, Hang Pan, Guanke Lv, Ye Li, Yanying Wang, Yukun Yang, Gaohong Zhu, Zhixu He, Xiangqing Zhu, Xinghua Pan
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Stem Cell Research & Therapy
Subjects:
Macaque
BMMSCs
Ovarian ageing
Online Access:https://doi.org/10.1186/s13287-021-02486-4

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