Optimization and characterization of antileukemic l-asparaginase produced by Fusarium solani endophyte

Optimization and characterization of antileukemic l-asparaginase produced by Fusarium solani endophyte

Abstract l-asparaginase is an antileukemic enzyme that hydrolyzes l-asparagine into l-aspartic acid and ammonia, causing cell starvation and apoptosis in susceptible leukemic cell populations. Currently, l-asparaginase obtained from bacterial sources is constrained by several issues, including lesse...

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Bibliographic Details
Main Authors: Sarah Osama, Moshera M. El-Sherei, Dalia A. Al-Mahdy, Mokhtar Bishr, Osama Salama, Marwa M. Raafat
Format: Article
Language:English
Published: SpringerOpen 2023-09-01
Series:AMB Express
Subjects:
l-asparaginase
Endophytes
Fusarium solani
Hedera helix
Optimization
Characterization
Online Access:https://doi.org/10.1186/s13568-023-01602-2

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