The composition of the dental pellicle: an updated literature review
BackgroundThe dental pellicle is a thin layer of up to several hundred nm in thickness, covering the tooth surface. It is known to protect the teeth from acid attacks through its selective permeability and it is involved in the remineralization process of the teeth. It functions also as binding site...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-10-01
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| Series: | Frontiers in Oral Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/froh.2023.1260442/full |
| _version_ | 1827795000900976640 |
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| author | Joachim Enax Bernhard Ganss Bennett T. Amaechi Erik Schulze zur Wiesche Frederic Meyer |
| author_facet | Joachim Enax Bernhard Ganss Bennett T. Amaechi Erik Schulze zur Wiesche Frederic Meyer |
| author_sort | Joachim Enax |
| collection | DOAJ |
| description | BackgroundThe dental pellicle is a thin layer of up to several hundred nm in thickness, covering the tooth surface. It is known to protect the teeth from acid attacks through its selective permeability and it is involved in the remineralization process of the teeth. It functions also as binding site and source of nutrients for bacteria and conditioning biofilm (foundation) for dental plaque formation.MethodsFor this updated literature review, the PubMed database was searched for the dental pellicle and its composition.ResultsThe dental pellicle has been analyzed in the past years with various state-of-the art analytic techniques such as high-resolution microscopic techniques (e.g., scanning electron microscopy, atomic force microscopy), spectrophotometry, mass spectrometry, affinity chromatography, enzyme-linked immunosorbent assays (ELISA), and blotting-techniques (e.g., western blot). It consists of several different amino acids, proteins, and proteolytic protein fragments. Some studies also investigated other compounds of the pellicle, mainly fatty acids, and carbohydrates.ConclusionsThe dental pellicle is composed mainly of different proteins, but also fatty acids, and carbohydrates. Analysis with state-of-the-art analytical techniques have uncovered mainly acidic proline-rich proteins, amylase, cystatin, immunoglobulins, lysozyme, and mucins as main proteins of the dental pellicle. The pellicle has protective properties for the teeth. Further research is necessary to gain more knowledge about the role of the pellicle in the tooth remineralization process. |
| first_indexed | 2024-03-11T18:42:56Z |
| format | Article |
| id | doaj.art-979c648d573e4e8e8b2af24132101a9a |
| institution | Directory Open Access Journal |
| issn | 2673-4842 |
| language | English |
| last_indexed | 2024-03-11T18:42:56Z |
| publishDate | 2023-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oral Health |
| spelling | doaj.art-979c648d573e4e8e8b2af24132101a9a2023-10-12T09:16:16ZengFrontiers Media S.A.Frontiers in Oral Health2673-48422023-10-01410.3389/froh.2023.12604421260442The composition of the dental pellicle: an updated literature reviewJoachim Enax0Bernhard Ganss1Bennett T. Amaechi2Erik Schulze zur Wiesche3Frederic Meyer4Research Department, Dr. Kurt Wolff GmbH & Co. KG, Bielefeld, GermanyFaculty of Dentistry, University of Toronto, Toronto, ON, CanadaDepartment of Comprehensive Dentistry, School of Dentistry, University of Texas Health San Antonio, San Antonio, TX, United StatesResearch Department, Dr. Kurt Wolff GmbH & Co. KG, Bielefeld, GermanyResearch Department, Dr. Kurt Wolff GmbH & Co. KG, Bielefeld, GermanyBackgroundThe dental pellicle is a thin layer of up to several hundred nm in thickness, covering the tooth surface. It is known to protect the teeth from acid attacks through its selective permeability and it is involved in the remineralization process of the teeth. It functions also as binding site and source of nutrients for bacteria and conditioning biofilm (foundation) for dental plaque formation.MethodsFor this updated literature review, the PubMed database was searched for the dental pellicle and its composition.ResultsThe dental pellicle has been analyzed in the past years with various state-of-the art analytic techniques such as high-resolution microscopic techniques (e.g., scanning electron microscopy, atomic force microscopy), spectrophotometry, mass spectrometry, affinity chromatography, enzyme-linked immunosorbent assays (ELISA), and blotting-techniques (e.g., western blot). It consists of several different amino acids, proteins, and proteolytic protein fragments. Some studies also investigated other compounds of the pellicle, mainly fatty acids, and carbohydrates.ConclusionsThe dental pellicle is composed mainly of different proteins, but also fatty acids, and carbohydrates. Analysis with state-of-the-art analytical techniques have uncovered mainly acidic proline-rich proteins, amylase, cystatin, immunoglobulins, lysozyme, and mucins as main proteins of the dental pellicle. The pellicle has protective properties for the teeth. Further research is necessary to gain more knowledge about the role of the pellicle in the tooth remineralization process.https://www.frontiersin.org/articles/10.3389/froh.2023.1260442/fulldental pellicleproteinssalivabiofilmteethhydroxyapatite |
| spellingShingle | Joachim Enax Bernhard Ganss Bennett T. Amaechi Erik Schulze zur Wiesche Frederic Meyer The composition of the dental pellicle: an updated literature review Frontiers in Oral Health dental pellicle proteins saliva biofilm teeth hydroxyapatite |
| title | The composition of the dental pellicle: an updated literature review |
| title_full | The composition of the dental pellicle: an updated literature review |
| title_fullStr | The composition of the dental pellicle: an updated literature review |
| title_full_unstemmed | The composition of the dental pellicle: an updated literature review |
| title_short | The composition of the dental pellicle: an updated literature review |
| title_sort | composition of the dental pellicle an updated literature review |
| topic | dental pellicle proteins saliva biofilm teeth hydroxyapatite |
| url | https://www.frontiersin.org/articles/10.3389/froh.2023.1260442/full |
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