Mass spectrometry imaging as a tool for evaluating the pulmonary distribution of exogenous surfactant in premature lambs

Abstract Background The amount of surfactant deposited in the lungs and its overall pulmonary distribution determine the therapeutic outcome of surfactant replacement therapy. Most of the currently available methods to determine the intrapulmonary distribution of surfactant are time-consuming and re...

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Bibliographic Details
Main Authors: Riccardo Zecchi, Pietro Franceschi, Laura Tigli, Francesca Ricci, Francesca Boscaro, Barbara Pioselli, Valentina Mileo, Xabier Murgia, Federico Bianco, Fabrizio Salomone, Augusto F. Schmidt, Noah H. Hillman, Matthew W. Kemp, Alan H. Jobe
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-019-1144-5