DESLORATADINE IN TREATMENT OF ALLERGIC RHINITIS: RESULTS OF RANDOMIZED, PLACEBO_CONTROLLED TRIAL

This review presents the results of randomized placebo controlled trial, aimed at studying the efficiency of modern non sedative antihistamine desloratadine in allergic rhinitis (AR). It is proven demonstratively that the application of desloratadine in comparison with placebo is accompanied by redu...

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Main Author: R.T. Saygitov
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2008-01-01
Series:Вопросы современной педиатрии
Online Access:https://vsp.spr-journal.ru/jour/article/view/1345
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author R.T. Saygitov
author_facet R.T. Saygitov
author_sort R.T. Saygitov
collection DOAJ
description This review presents the results of randomized placebo controlled trial, aimed at studying the efficiency of modern non sedative antihistamine desloratadine in allergic rhinitis (AR). It is proven demonstratively that the application of desloratadine in comparison with placebo is accompanied by reduction in total symptoms scores, total nasal symptoms score and improvement in nasal airflow patency. In addition, the advantage of desloratadine versus placebo was established for reducing of nasal eosinophil levels. The acquired data confirm that the efficiency of desloratadine for AR corresponds to IA level of evidence.Key words: desloratadine, allergic rhinitis, randomizeplacebo_controlled trial.
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spelling doaj.art-97a4676b2a484f3197a894b09117f9e72023-09-03T09:26:58Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352008-01-017182901345DESLORATADINE IN TREATMENT OF ALLERGIC RHINITIS: RESULTS OF RANDOMIZED, PLACEBO_CONTROLLED TRIALR.T. Saygitov0Научный центр здоровья детей РАМН, МоскваThis review presents the results of randomized placebo controlled trial, aimed at studying the efficiency of modern non sedative antihistamine desloratadine in allergic rhinitis (AR). It is proven demonstratively that the application of desloratadine in comparison with placebo is accompanied by reduction in total symptoms scores, total nasal symptoms score and improvement in nasal airflow patency. In addition, the advantage of desloratadine versus placebo was established for reducing of nasal eosinophil levels. The acquired data confirm that the efficiency of desloratadine for AR corresponds to IA level of evidence.Key words: desloratadine, allergic rhinitis, randomizeplacebo_controlled trial.https://vsp.spr-journal.ru/jour/article/view/1345
spellingShingle R.T. Saygitov
DESLORATADINE IN TREATMENT OF ALLERGIC RHINITIS: RESULTS OF RANDOMIZED, PLACEBO_CONTROLLED TRIAL
Вопросы современной педиатрии
title DESLORATADINE IN TREATMENT OF ALLERGIC RHINITIS: RESULTS OF RANDOMIZED, PLACEBO_CONTROLLED TRIAL
title_full DESLORATADINE IN TREATMENT OF ALLERGIC RHINITIS: RESULTS OF RANDOMIZED, PLACEBO_CONTROLLED TRIAL
title_fullStr DESLORATADINE IN TREATMENT OF ALLERGIC RHINITIS: RESULTS OF RANDOMIZED, PLACEBO_CONTROLLED TRIAL
title_full_unstemmed DESLORATADINE IN TREATMENT OF ALLERGIC RHINITIS: RESULTS OF RANDOMIZED, PLACEBO_CONTROLLED TRIAL
title_short DESLORATADINE IN TREATMENT OF ALLERGIC RHINITIS: RESULTS OF RANDOMIZED, PLACEBO_CONTROLLED TRIAL
title_sort desloratadine in treatment of allergic rhinitis results of randomized placebo controlled trial
url https://vsp.spr-journal.ru/jour/article/view/1345
work_keys_str_mv AT rtsaygitov desloratadineintreatmentofallergicrhinitisresultsofrandomizedplacebocontrolledtrial