Liposome and Their Applications in Cancer Therapy
ABSTRACT Liposomes, the vesicles of phospholipid bilayer, can encapsulate both hydrophilic and lipophilic drugs and protect them from degradation. Liposomes have been extensively studied and continue to create intense interest in research since their discovery in the mid-1960s. Since then, liposomes...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Instituto de Tecnologia do Paraná (Tecpar)
2016-01-01
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| Series: | Brazilian Archives of Biology and Technology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100303&lng=en&tlng=en |
| _version_ | 1798045985737277440 |
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| author | Himanshu Pandey Radha Rani Vishnu Agarwal |
| author_facet | Himanshu Pandey Radha Rani Vishnu Agarwal |
| author_sort | Himanshu Pandey |
| collection | DOAJ |
| description | ABSTRACT Liposomes, the vesicles of phospholipid bilayer, can encapsulate both hydrophilic and lipophilic drugs and protect them from degradation. Liposomes have been extensively studied and continue to create intense interest in research since their discovery in the mid-1960s. Since then, liposomes have been considered to be the most successful nanocarriers for drug deliver and have made their way to the market. Currently, a number of liposomal formulations are on the marker for cancer treatment and many more are in pipe line. This review discusses about the liposome components, methods of preparation, drug encapsulation mechanism and the potential therapeutic applications of liposomes in cancer therapy. |
| first_indexed | 2024-04-11T23:31:32Z |
| format | Article |
| id | doaj.art-97a791db158b4d5aa10862870b3a7947 |
| institution | Directory Open Access Journal |
| issn | 1678-4324 |
| language | English |
| last_indexed | 2024-04-11T23:31:32Z |
| publishDate | 2016-01-01 |
| publisher | Instituto de Tecnologia do Paraná (Tecpar) |
| record_format | Article |
| series | Brazilian Archives of Biology and Technology |
| spelling | doaj.art-97a791db158b4d5aa10862870b3a79472022-12-22T03:57:08ZengInstituto de Tecnologia do Paraná (Tecpar)Brazilian Archives of Biology and Technology1678-43242016-01-0159010.1590/1678-4324-2016150477S1516-89132016000100303Liposome and Their Applications in Cancer TherapyHimanshu PandeyRadha RaniVishnu AgarwalABSTRACT Liposomes, the vesicles of phospholipid bilayer, can encapsulate both hydrophilic and lipophilic drugs and protect them from degradation. Liposomes have been extensively studied and continue to create intense interest in research since their discovery in the mid-1960s. Since then, liposomes have been considered to be the most successful nanocarriers for drug deliver and have made their way to the market. Currently, a number of liposomal formulations are on the marker for cancer treatment and many more are in pipe line. This review discusses about the liposome components, methods of preparation, drug encapsulation mechanism and the potential therapeutic applications of liposomes in cancer therapy.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100303&lng=en&tlng=enLiposomesDrug deliveryCancerDoxilLipoDoxMyocet |
| spellingShingle | Himanshu Pandey Radha Rani Vishnu Agarwal Liposome and Their Applications in Cancer Therapy Brazilian Archives of Biology and Technology Liposomes Drug delivery Cancer Doxil LipoDox Myocet |
| title | Liposome and Their Applications in Cancer Therapy |
| title_full | Liposome and Their Applications in Cancer Therapy |
| title_fullStr | Liposome and Their Applications in Cancer Therapy |
| title_full_unstemmed | Liposome and Their Applications in Cancer Therapy |
| title_short | Liposome and Their Applications in Cancer Therapy |
| title_sort | liposome and their applications in cancer therapy |
| topic | Liposomes Drug delivery Cancer Doxil LipoDox Myocet |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100303&lng=en&tlng=en |
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