A solid variant of splenic mesothelial cyst, a case report with molecular analysis

Cystic lesions of the spleen are rare and challenging to diagnose, often generating a broad differential diagnosis. However, a comprehensive approach which includes molecular studies, may result in an accurate diagnosis and further provide insight into underlying etiologies. In this study, we report...

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Main Authors: Ekin Guney, Kwun Wah Wen, Roberto Ruiz-Cordero, Linda Ferrell, Ryan M. Gill, Dennis O'Malley, Kirk D. Jones, Robert Ohgami
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Human Pathology: Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214330021000389
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author Ekin Guney
Kwun Wah Wen
Roberto Ruiz-Cordero
Linda Ferrell
Ryan M. Gill
Dennis O'Malley
Kirk D. Jones
Robert Ohgami
author_facet Ekin Guney
Kwun Wah Wen
Roberto Ruiz-Cordero
Linda Ferrell
Ryan M. Gill
Dennis O'Malley
Kirk D. Jones
Robert Ohgami
author_sort Ekin Guney
collection DOAJ
description Cystic lesions of the spleen are rare and challenging to diagnose, often generating a broad differential diagnosis. However, a comprehensive approach which includes molecular studies, may result in an accurate diagnosis and further provide insight into underlying etiologies. In this study, we report an extensive analysis of a rare solid variant of splenic mesothelial cyst by utilizing clinical, imaging, gross, histopathologic, immunohistochemical and molecular findings.
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spelling doaj.art-97ac155f4ec24abebf3f63a6605376962022-12-21T22:11:08ZengElsevierHuman Pathology: Case Reports2214-33002021-06-0124200509A solid variant of splenic mesothelial cyst, a case report with molecular analysisEkin Guney0Kwun Wah Wen1Roberto Ruiz-Cordero2Linda Ferrell3Ryan M. Gill4Dennis O'Malley5Kirk D. Jones6Robert Ohgami7University of California San Francisco, Department of Pathology, United States; Corresponding author at: University of California, San Francisco, 505 Parnassus Ave, San Francisco, CA 94143, United States.University of California San Francisco, Department of Pathology, United StatesUniversity of California San Francisco, Department of Pathology, United StatesUniversity of California San Francisco, Department of Pathology, United StatesUniversity of California San Francisco, Department of Pathology, United StatesNeoGenomics, NeoGenomics CA, United StatesUniversity of California San Francisco, Department of Pathology, United StatesUniversity of California San Francisco, Department of Pathology, United StatesCystic lesions of the spleen are rare and challenging to diagnose, often generating a broad differential diagnosis. However, a comprehensive approach which includes molecular studies, may result in an accurate diagnosis and further provide insight into underlying etiologies. In this study, we report an extensive analysis of a rare solid variant of splenic mesothelial cyst by utilizing clinical, imaging, gross, histopathologic, immunohistochemical and molecular findings.http://www.sciencedirect.com/science/article/pii/S2214330021000389Mesothelial cystNext generation sequencing
spellingShingle Ekin Guney
Kwun Wah Wen
Roberto Ruiz-Cordero
Linda Ferrell
Ryan M. Gill
Dennis O'Malley
Kirk D. Jones
Robert Ohgami
A solid variant of splenic mesothelial cyst, a case report with molecular analysis
Human Pathology: Case Reports
Mesothelial cyst
Next generation sequencing
title A solid variant of splenic mesothelial cyst, a case report with molecular analysis
title_full A solid variant of splenic mesothelial cyst, a case report with molecular analysis
title_fullStr A solid variant of splenic mesothelial cyst, a case report with molecular analysis
title_full_unstemmed A solid variant of splenic mesothelial cyst, a case report with molecular analysis
title_short A solid variant of splenic mesothelial cyst, a case report with molecular analysis
title_sort solid variant of splenic mesothelial cyst a case report with molecular analysis
topic Mesothelial cyst
Next generation sequencing
url http://www.sciencedirect.com/science/article/pii/S2214330021000389
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