Rutin inhibits DRP1-mediated mitochondrial fission and prevents ethanol-induced hepatotoxicity in HepG2 cells and zebrafish

Rutin inhibits DRP1-mediated mitochondrial fission and prevents ethanol-induced hepatotoxicity in HepG2 cells and zebrafish

Excessive alcohol consumption causes the cellular and tissue damage. The toxic metabolites of ethanol are harmful to multiple organ systems, such as the central nervous system, skeletal muscles, and liver, and cause alcohol-induced diseases like cancer, as well as induce hepatotoxicity, and alcoholi...

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Bibliographic Details
Main Authors: Youngsook Choi, Heymin Seo, Mina Cho, Joohee Kim, Hak Suk Chung, Icksoo Lee, Min Jung Kim
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Animal Cells and Systems
Subjects:
rutin
ethanol
drp1
zebrafish
mitochondria
Online Access:http://dx.doi.org/10.1080/19768354.2021.1882565

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