A viral discovery methodology for clinical biopsy samples utilising massively parallel next generation sequencing.

A viral discovery methodology for clinical biopsy samples utilising massively parallel next generation sequencing.

Here we describe a virus discovery protocol for a range of different virus genera, that can be applied to biopsy-sized tissue samples. Our viral enrichment procedure, validated using canine and human liver samples, significantly improves viral read copy number and increases the length of viral conti...

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Bibliographic Details
Main Authors: Gordon M Daly, Nick Bexfield, Judith Heaney, Sam Stubbs, Antonia P Mayer, Anne Palser, Paul Kellam, Nizar Drou, Mario Caccamo, Laurence Tiley, Graeme J M Alexander, William Bernal, Jonathan L Heeney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3244418?pdf=render

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