Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients

Adane Tesfaye,1 Haileyesus Josef,1 Temesgen Bizuayehu Wube,2 Zeleke Girma,1 Belay Negasa,1 Temesgen Muche,1 Bewnetu Zewude3 1Department of Public Health, School of Public Health, College of Medicine and Health Science, Dilla University, Dilla, Ethiopia; 2School of Medical Laboratory Science, College...

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Main Authors: Tesfaye A, Josef H, Wube TB, Girma Z, Negasa B, Muche T, Zewude B
Format: Article
Language:English
Published: Dove Medical Press 2020-11-01
Series:Diabetes, Metabolic Syndrome and Obesity
Subjects:
Online Access:https://www.dovepress.com/magnitude-of-and-factors-associated-with-cardiovascular-disease-among--peer-reviewed-article-DMSO
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author Tesfaye A
Josef H
Wube TB
Girma Z
Negasa B
Muche T
Zewude B
author_facet Tesfaye A
Josef H
Wube TB
Girma Z
Negasa B
Muche T
Zewude B
author_sort Tesfaye A
collection DOAJ
description Adane Tesfaye,1 Haileyesus Josef,1 Temesgen Bizuayehu Wube,2 Zeleke Girma,1 Belay Negasa,1 Temesgen Muche,1 Bewnetu Zewude3 1Department of Public Health, School of Public Health, College of Medicine and Health Science, Dilla University, Dilla, Ethiopia; 2School of Medical Laboratory Science, College of Medicine and Health Science, Hawassa University, Hawassa, Ethiopia; 3Department of Sociology, College of Social Science, Wolaita Sodo University, Wolaita Sodo, EthiopiaCorrespondence: Temesgen Bizuayehu WubeSchool of Medical Laboratory Science, College of Medicine and Health Science, Hawassa University, P.o Box 1560, Hawassa, EthiopiaTel +2519-16-60-45-51Email temesgenbuizuayehu2@gmail.comBackground: Diabetes mellitus is becoming one of the major health problems in developing countries. The number of adults living with type 2 diabetes mellitus (T2DM) worldwide is increasing over time. Cardiovascular disease (CVD) is the major cause of death in T2DM. The objective of this study was to determine the prevalence of cardiovascular disease and its associated factors among diabetic patients at the MRC clinic of Dilla University Referral Hospital (DURH).Methods: A hospital-based cross-sectional study was conducted from April to May 2019 . A total of 216 diabetic individuals were selected with a convenient sampling technique from patients on follow-up at DURH MRC. Data were collected using a structured format. The diagnosis of CVD was made with the necessary diagnostic tests and examination. The data analysis was done in SPSS software version 20. Bivariate and multivariable logistic regression analysis was carried out to identify factors associated with cardiovascular disease.Results: A total of 216 patients participated in the study and the mean age of the study participants was 30 years; 83.3% of the study participants were male. The overall prevalence of cardiovascular disease was 25% of which 57% were ischemic heart disease, 32% were hypertensive and 10% were stroke. Duration of DM for more than 10 years and diabetic drug discontinuation were factors associated with cardiovascular disease. Odds of CVD was nearly four times more in those whose duration of DM is more than 10 years (AOR=4.00, 95% CI: 2.386– 6.705) and odds of CVD among those who discontinued medication were almost three times more, (AOR=2.98, 95% CI: 1.287– 6.080).Conclusion: A quarter of the diabetic population studied developed CVD. Duration of DM for more than 10 years and drug discontinuation are independent associated factors of CVD. Hence appropriate intervention at early stages should be implemented at primary healthcare level.Keywords: T2DM, cardiovascular disease, Ethiopia
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spelling doaj.art-97bd2f8a8aaa4f0da65db3134eb4fca92023-02-02T10:26:15ZengDove Medical PressDiabetes, Metabolic Syndrome and Obesity1178-70072020-11-01Volume 134123412958892Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus PatientsTesfaye AJosef HWube TBGirma ZNegasa BMuche TZewude BAdane Tesfaye,1 Haileyesus Josef,1 Temesgen Bizuayehu Wube,2 Zeleke Girma,1 Belay Negasa,1 Temesgen Muche,1 Bewnetu Zewude3 1Department of Public Health, School of Public Health, College of Medicine and Health Science, Dilla University, Dilla, Ethiopia; 2School of Medical Laboratory Science, College of Medicine and Health Science, Hawassa University, Hawassa, Ethiopia; 3Department of Sociology, College of Social Science, Wolaita Sodo University, Wolaita Sodo, EthiopiaCorrespondence: Temesgen Bizuayehu WubeSchool of Medical Laboratory Science, College of Medicine and Health Science, Hawassa University, P.o Box 1560, Hawassa, EthiopiaTel +2519-16-60-45-51Email temesgenbuizuayehu2@gmail.comBackground: Diabetes mellitus is becoming one of the major health problems in developing countries. The number of adults living with type 2 diabetes mellitus (T2DM) worldwide is increasing over time. Cardiovascular disease (CVD) is the major cause of death in T2DM. The objective of this study was to determine the prevalence of cardiovascular disease and its associated factors among diabetic patients at the MRC clinic of Dilla University Referral Hospital (DURH).Methods: A hospital-based cross-sectional study was conducted from April to May 2019 . A total of 216 diabetic individuals were selected with a convenient sampling technique from patients on follow-up at DURH MRC. Data were collected using a structured format. The diagnosis of CVD was made with the necessary diagnostic tests and examination. The data analysis was done in SPSS software version 20. Bivariate and multivariable logistic regression analysis was carried out to identify factors associated with cardiovascular disease.Results: A total of 216 patients participated in the study and the mean age of the study participants was 30 years; 83.3% of the study participants were male. The overall prevalence of cardiovascular disease was 25% of which 57% were ischemic heart disease, 32% were hypertensive and 10% were stroke. Duration of DM for more than 10 years and diabetic drug discontinuation were factors associated with cardiovascular disease. Odds of CVD was nearly four times more in those whose duration of DM is more than 10 years (AOR=4.00, 95% CI: 2.386– 6.705) and odds of CVD among those who discontinued medication were almost three times more, (AOR=2.98, 95% CI: 1.287– 6.080).Conclusion: A quarter of the diabetic population studied developed CVD. Duration of DM for more than 10 years and drug discontinuation are independent associated factors of CVD. Hence appropriate intervention at early stages should be implemented at primary healthcare level.Keywords: T2DM, cardiovascular disease, Ethiopiahttps://www.dovepress.com/magnitude-of-and-factors-associated-with-cardiovascular-disease-among--peer-reviewed-article-DMSOt2dmcardiovascular diseaseethiopia
spellingShingle Tesfaye A
Josef H
Wube TB
Girma Z
Negasa B
Muche T
Zewude B
Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients
Diabetes, Metabolic Syndrome and Obesity
t2dm
cardiovascular disease
ethiopia
title Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients
title_full Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients
title_fullStr Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients
title_full_unstemmed Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients
title_short Magnitude of, and Factors Associated with Cardiovascular Disease Among Type Two Diabetes Mellitus Patients
title_sort magnitude of and factors associated with cardiovascular disease among type two diabetes mellitus patients
topic t2dm
cardiovascular disease
ethiopia
url https://www.dovepress.com/magnitude-of-and-factors-associated-with-cardiovascular-disease-among--peer-reviewed-article-DMSO
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