Polymorphism of 8 X-Chromosomal STR loci in Turkish population
In forensic sciences, X-chromosomal short tandem repeats (X-STRs), a complementary marker to the other genetic markers (autosomal, Y-chromosomal or mitochondrial), can be used in complex kinship analysis. Especially when a biological sample is not available from the putative father and samples from...
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| Format: | Article |
| Language: | English |
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Society of Turaz Bilim
2018-09-01
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| Series: | Medicine Science |
| Subjects: | |
| Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=287952 |
| _version_ | 1797329240328241152 |
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| author | Erhan Acar Gonul Filoglu Ozlem Bulbul |
| author_facet | Erhan Acar Gonul Filoglu Ozlem Bulbul |
| author_sort | Erhan Acar |
| collection | DOAJ |
| description | In forensic sciences, X-chromosomal short tandem repeats (X-STRs), a complementary marker to the other genetic markers (autosomal, Y-chromosomal or mitochondrial), can be used in complex kinship analysis. Especially when a biological sample is not available from the putative father and samples from paternal relatives could be used instead. In this study eight X-chromosomal STR loci (DXS7132, DXS7423, DXS8378, DXS10074, DXS10101, DXS10134, DXS10135, HPRTB and Amelogenin) were investigated in population samples of 129 unrelated healthy Turkish volunteer [male (n=56), female (n=73)]. X-STRs were amplified in a multiplex PCR reaction with Mentype® Argus X-8 Kit. The separation and detection of PCR products were performed by capillary electrophoresis on a 310 Genetic Analyzer (Applied Biosystems). Statistical analysis was performed using POPgene v.1.32. and Arlequin v3.1 softwares. Data was compared with Turkish populations living in Europe (Germany and Denmark) and other populations (Japan, Ghana, Finland, Portugal and Germany). The high genetic distances were observed for the geographically distant populations while no significant differences found between in studied and tested Turkish populations. Results showed that eight STR loci on the X chromosome in Turkish population were found as highly polymorphic and useful for forensic applications. [Med-Science 2018; 7(3.000): 672-6] |
| first_indexed | 2024-03-08T07:02:55Z |
| format | Article |
| id | doaj.art-97bec0ceb0a543249534085244e40baa |
| institution | Directory Open Access Journal |
| issn | 2147-0634 |
| language | English |
| last_indexed | 2024-03-08T07:02:55Z |
| publishDate | 2018-09-01 |
| publisher | Society of Turaz Bilim |
| record_format | Article |
| series | Medicine Science |
| spelling | doaj.art-97bec0ceb0a543249534085244e40baa2024-02-03T05:37:05ZengSociety of Turaz BilimMedicine Science2147-06342018-09-0173672610.5455/medscience.2018.07.8778287952Polymorphism of 8 X-Chromosomal STR loci in Turkish populationErhan Acar0Gonul FilogluOzlem BulbulIstanbul University, Institute of Forensic Sciences, Istanbul, TurkeyIn forensic sciences, X-chromosomal short tandem repeats (X-STRs), a complementary marker to the other genetic markers (autosomal, Y-chromosomal or mitochondrial), can be used in complex kinship analysis. Especially when a biological sample is not available from the putative father and samples from paternal relatives could be used instead. In this study eight X-chromosomal STR loci (DXS7132, DXS7423, DXS8378, DXS10074, DXS10101, DXS10134, DXS10135, HPRTB and Amelogenin) were investigated in population samples of 129 unrelated healthy Turkish volunteer [male (n=56), female (n=73)]. X-STRs were amplified in a multiplex PCR reaction with Mentype® Argus X-8 Kit. The separation and detection of PCR products were performed by capillary electrophoresis on a 310 Genetic Analyzer (Applied Biosystems). Statistical analysis was performed using POPgene v.1.32. and Arlequin v3.1 softwares. Data was compared with Turkish populations living in Europe (Germany and Denmark) and other populations (Japan, Ghana, Finland, Portugal and Germany). The high genetic distances were observed for the geographically distant populations while no significant differences found between in studied and tested Turkish populations. Results showed that eight STR loci on the X chromosome in Turkish population were found as highly polymorphic and useful for forensic applications. [Med-Science 2018; 7(3.000): 672-6]http://www.ejmanager.com/fulltextpdf.php?mno=287952X-STRkinship analysisTurkish population |
| spellingShingle | Erhan Acar Gonul Filoglu Ozlem Bulbul Polymorphism of 8 X-Chromosomal STR loci in Turkish population Medicine Science X-STR kinship analysis Turkish population |
| title | Polymorphism of 8 X-Chromosomal STR loci in Turkish population |
| title_full | Polymorphism of 8 X-Chromosomal STR loci in Turkish population |
| title_fullStr | Polymorphism of 8 X-Chromosomal STR loci in Turkish population |
| title_full_unstemmed | Polymorphism of 8 X-Chromosomal STR loci in Turkish population |
| title_short | Polymorphism of 8 X-Chromosomal STR loci in Turkish population |
| title_sort | polymorphism of 8 x chromosomal str loci in turkish population |
| topic | X-STR kinship analysis Turkish population |
| url | http://www.ejmanager.com/fulltextpdf.php?mno=287952 |
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