Protofibrils of amyloid β-protein inhibit specific K+ currents in neocortical cultures

Protofibrils (PFs) are recently described intermediate assemblies formed during the fibrillogenesis of amyloidogenic proteins and may play an important pathogenic role in Parkinson’s and Alzheimer’s disease (AD). Here we show for the first time that amyloid β-protein (Aβ) attenuation of specific K+...

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Bibliographic Details
Main Authors: Chian P Ye, Dennis J Selkoe, Dean M Hartley
Format: Article
Language:English
Published: Elsevier 2003-08-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103000688

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