Protofibrils of amyloid β-protein inhibit specific K+ currents in neocortical cultures
Protofibrils (PFs) are recently described intermediate assemblies formed during the fibrillogenesis of amyloidogenic proteins and may play an important pathogenic role in Parkinson’s and Alzheimer’s disease (AD). Here we show for the first time that amyloid β-protein (Aβ) attenuation of specific K+...
Main Authors: | Chian P Ye, Dennis J Selkoe, Dean M Hartley |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2003-08-01
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Series: | Neurobiology of Disease |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996103000688 |
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